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Healthy Volunteers clinical trials

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NCT ID: NCT05732194 Recruiting - Healthy Volunteers Clinical Trials

Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers

Start date: January 18, 2023
Phase: Phase 1
Study type: Interventional

The study will be conducted as a single-center, randomized, double-blind, placebo-controlled, ascending dose study in up to 4 sequential cohorts of healthy subjects. Each cohort will enroll 8 subjects: 6 subjects will receive ITI-333 and 2 subjects will receive placebo once daily for 14 days.

NCT ID: NCT05731843 Completed - Clinical trials for Healthy Volunteer Study

Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir

AT-527
Start date: January 30, 2023
Phase: Phase 1
Study type: Interventional

Drug-drug interaction study of Ruzasvir and Bemnifosbuvir

NCT ID: NCT05730842 Completed - Healthy Volunteer Clinical Trials

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Start date: January 12, 2023
Phase: Phase 1
Study type: Interventional

This is a Phase 1 2-part, single-center, open-label study in healthy male volunteers. Part A will assess the absorption, metabolism, excretion, and pharmacokinetics of one oral dose of radiolabeled EDG-5506. Part B will assess bioavailability of EDG-5506 with a single oral dose of EDG-5506 and a single intravenous dose of radiolabeled EDG-5506.

NCT ID: NCT05729594 Completed - Healthy Volunteers Clinical Trials

Systemic Pharmacokinetic Study of T4032 (Unpreserved Bimatoprost 0.01%) Eye Gel Versus Lumigan® 0.01% Eye Drops in 40 Healthy Volunteers

Start date: February 27, 2023
Phase: Phase 1
Study type: Interventional

This study is being performed to compare the systemic pharmacokinetic profiles of T4032 and Lumigan 0.01% given that T4032 has a different formulation (in terms of excipients) from the reference product.

NCT ID: NCT05729386 Recruiting - Healthy Volunteers Clinical Trials

A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions

Start date: February 6, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and pharmacokinetics of oral administration of GC2129A in fed conditions to healthy adult volunteers.

NCT ID: NCT05726851 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Participants

Start date: February 6, 2023
Phase: Phase 1
Study type: Interventional

The primary purpose of the study is to evaluate the safety and tolerability of single intravenous (IV) infusions of E2025 in healthy adult participants.

NCT ID: NCT05725252 Completed - Healthy Volunteers Clinical Trials

To Evaluate the Safety and the Pharmacokinetics of NVP-2203

Start date: May 28, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and pharmacokinetics after administration of NVP-2203.

NCT ID: NCT05724797 Recruiting - Healthy Volunteers Clinical Trials

Single Ascending Dose Study of NRS 033 in Healthy Volunteers

Start date: April 17, 2023
Phase: Phase 1
Study type: Interventional

This is a phase 1, first in human, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study in healthy adult male and female subjects 18 to 55 years of age, inclusive.

NCT ID: NCT05724693 Recruiting - Healthy Volunteer Clinical Trials

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Start date: January 30, 2023
Phase: Phase 1
Study type: Interventional

To Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Bemnifosbuvir After a Single Dose

NCT ID: NCT05723692 Completed - Healthy Volunteers Clinical Trials

A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers

Start date: January 17, 2023
Phase: Phase 1
Study type: Interventional

This study with ALTB-268 will determine the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple ascending doses of ALTB-268 in healthy volunteers.