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Healthy Volunteers clinical trials

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NCT ID: NCT05729594 Completed - Healthy Volunteers Clinical Trials

Systemic Pharmacokinetic Study of T4032 (Unpreserved Bimatoprost 0.01%) Eye Gel Versus Lumigan® 0.01% Eye Drops in 40 Healthy Volunteers

Start date: February 27, 2023
Phase: Phase 1
Study type: Interventional

This study is being performed to compare the systemic pharmacokinetic profiles of T4032 and Lumigan 0.01% given that T4032 has a different formulation (in terms of excipients) from the reference product.

NCT ID: NCT05726851 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Participants

Start date: February 6, 2023
Phase: Phase 1
Study type: Interventional

The primary purpose of the study is to evaluate the safety and tolerability of single intravenous (IV) infusions of E2025 in healthy adult participants.

NCT ID: NCT05725252 Completed - Healthy Volunteers Clinical Trials

To Evaluate the Safety and the Pharmacokinetics of NVP-2203

Start date: May 28, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and pharmacokinetics after administration of NVP-2203.

NCT ID: NCT05723692 Completed - Healthy Volunteers Clinical Trials

A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers

Start date: January 17, 2023
Phase: Phase 1
Study type: Interventional

This study with ALTB-268 will determine the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple ascending doses of ALTB-268 in healthy volunteers.

NCT ID: NCT05722158 Completed - Healthy Volunteers Clinical Trials

Bioavailability of Different Collagen-based Treatments After Oral Intake

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate the postprandial absorption of collagen and elucidate the absorption rate and bioavailability after oral intake of collagen-based products. Participants will be asked to drink solutions containing the study products (one product per group, a total of four products), and blood samples will be obtained by digital puncture at different time points. Plasma will be collected and a set of collagen-derived amino acids, di-peptides and tri-peptides will be quantified by LC-MS. Each product will be compared to the placebo group.

NCT ID: NCT05691699 Completed - Healthy Volunteer Clinical Trials

A Study to Assess Adverse Events and How Single and Multiple Ascending Doses of ABBV-903 Move Through the Body in Healthy Adults

Start date: January 3, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate adverse events and tolerability of single and multiple doses of ABBV-903, and to assess how the drug moves through the body in healthy adult volunteers.

NCT ID: NCT05688098 Completed - Healthy Volunteers Clinical Trials

Pharmacokinetics of Irbesartan/Amlodipine High FDC and Co-administration of Irbesartan and Amlodipine High in Healthy Volunteers

Start date: September 23, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare pharmacokinetics and safety of Irbesartan and Amlodipine High Fixed Dose Combination and coadministration of mono compounds in healthy adult volunteers

NCT ID: NCT05688085 Completed - Healthy Volunteers Clinical Trials

Pharmacokinetics of Irbesartan High/Amlodipine FDC and Co-administration of Irbesartan High and Amlodipine in Healthy Volunteers

Start date: October 18, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare pharmacokinetics and safety of Irbesartan High and Amlodipine Fixed Dose Combination and coadministration of mono compounds in healthy adult volunteers

NCT ID: NCT05686980 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Adverse Events and How Oral ABBV-552 Capsules Moves Through the Body of Healthy Adult Japanese and Han Chinese Participants

Start date: January 17, 2023
Phase: Phase 1
Study type: Interventional

This study will assess how safe ABBV-552 is and how ABBV-552 moves through the body of adult healthy Japanese and Han Chinese participants. Adverse Events will be assessed. ABBV-552 is an investigational drug being developed for potential treatment of Alzheimer's disease (AD). Approximately 18 adult healthy Japanese and Han Chinese volunteers will be enrolled in 2 sites in the United States. Japanese participants assigned to Arm 1 will receive ascending doses of ABBV-552 oral capsules once every week for 3 weeks. Han Chinese participants assigned to Arm 2 will receive oral ABBV-552 capsules on Day 1. All participants will be followed for 30 days after their last dose. Participants will be confined for 22 days or 8 days depending on the Arm they are assigned to. Adverse Events and blood tests will be performed.

NCT ID: NCT05686291 Completed - Healthy Volunteer Clinical Trials

Effectiveness of Hybrid Learning Mode of Volunteer Training

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

As the effectiveness of the hybrid volunteer training in Hong Kong is under-studied, this experimental study aims to develop a hybrid learning mode of volunteer training that increase volunteering-related self-efficacy and its associated outcomes among volunteer. In particular, this study compares the efficacy of hybrid volunteer training with the wait-list control group. The volunteer training will consist of a 6-module online course, followed by 5 face-to-face courses. Each module will consist of the key volunteer training component presented in in written or video format. Materials will be presented interactively to facilitate engagement.