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Clinical Trial Summary

The purpose of this study is to compare the mucointegration of 2 types of surface roughness of zirconia abutments with titanium. The surface roughness will be machined and ultra-polished.


Clinical Trial Description

After being informed about the study and potential risks, all participants give written informed consent and eligibility for study entry. The day of the surgery, patients will be randomized in machined zirconia or ultra-polished zirconia. After 8 weeks of healing, biopsy are separated in two groups according to the removal: - if the abutment come together with the surrounding soft tissues, it goes for a non decalcified histology for histometric measurements to determine the dimensions of biological width (sulcus depth, epithelial and connective adhesion) - if the abutment come separate of the surrounding tissue, the soft tissue goes for immunohistochemistry to analyse pro-inflammatory cells and vascularisation and the abutment for SEM analysis to calculate the percentage of adhesion of the cells on the abutment ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05805033
Study type Interventional
Source Centre Hospitalier Universitaire de Liege
Contact Clémentine Canuel, MsD
Phone +33679097264
Email clementine.canuel@hotmail.fr
Status Recruiting
Phase N/A
Start date September 22, 2023
Completion date September 1, 2024

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