Influence of Different Ankle Positions on Nerve Conduction Parameters of Deep Peroneal Nerve

Healthy Subjects Clinical Trial

Official title:

Influence of Different Ankle Positions on Nerve Conduction Parameters of Deep Peroneal Nerve

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05635721
• Other study ID #: P.T.REC/012/004076
• Status: Completed
• Start date: December 5, 2022
• Est. completion date: January 26, 2023

Study information

• Verified date: January 2023
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

BACKGROUND:

The deep peroneal nerve arises as a branch of the common peroneal nerve which courses around the neck of the fibula. The motor component of deep peroneal nerve is responsible for innervating the anterior compartment of the lower leg which includes the tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus tertius muscles.

Nerve conduction velocity shortly known as "NCV" tests are used determine the speed of the electrical signals moving along a specific peripheral nerve .This will be helpful in localizing the site of entrapment of peripheral nerves and useful for assessing both recovery and prognosis of any injury to peripheral nervesthere are numerous aspects that could influence nerve conduction study.

Although changes in joint position have been reported in several studies to affect nerve conduction velocity of peripheral nerves. the effect of changing ankle joint position on deep peroneal NCV has not been repor Purpose

This study will investigate the effect of different ankle positions on:

1. Deep peroneal nerve distal motor latency across ankle joint.

2. Deep peroneal nerve sensory onset latency across ankle joint

Description:

31healthy subjects of both genders with age ranging from 20to 40years old were examined for motor distal latency and sensory onset latency at three different ankle positions :neutral,20degrees dorsiflexion and 40degrees plantar flexion

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: January 26, 2023
• Est. primary completion date: January 3, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion criteria:

• Healthy subjects.

• Age ranges from 20 to 40 years because longer latencies and slower nerve conduction velocity are seen significantly with increasing age.

• All participants will be selected with body mass index (BMI) between 18.5 and 24.9kg/cm2 .

Exclusion criteria:

• Elderly subjects.

• Pregnant women.

• Subjects with history of or risk factors for peripheral nerve lesions.

• Obese subjects.

• Subjects with any foot deformity.

• History of lower limb fractures.

• History of surgery to lower limbs

• Diabetic patients.

• Patients with cardiovascular disorders.

• Hypertensive patients.

• Women wearing high heeled shoes.

Related Conditions & MeSH terms

• Healthy Subjects

Locations

Country	Name	City	State
Egypt	Mahmoud Salah	Aga

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Deep peroneal nerve motor distal latency	Motor distal latency: It is the time between the distal stimulus and the onset of compound muscle action potential(CMAP)at recording muscles	30 minutes for each participant
Primary	Deep peroneal nerve sensory onset latency	: It is the time taken from the stimulus artifact to the initial negative deflection of the sensory nerve action potential (SNAP)	30 minutes for each participant