Effect of Oat Compounds on Postprandial Glucose Response

Healthy Subjects Clinical Trial

Official title:

Synergistic Effect of Oat Beta-glucans and Oat Polar Lipids on Postprandial Glucose Response

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05177172
• Other study ID #: Scanoats
• Status: Completed
• Phase: N/A
• Start date: December 1, 2021
• Est. completion date: January 19, 2022

Study information

• Verified date: January 2022
• Source: Lund University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this project we will investigate synergistic effects of oat polar lipids and beta glucans on postprandial glucose tolerance

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: January 19, 2022
• Est. primary completion date: January 19, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• healthy

• BMI 20-28 kg/m2

• Diet which follows the Nordic Nutrition Recommendations (non-vegetarian)

Exclusion Criteria:

• fasting glucose > 6.1 mmol/L

• metabolic diseases

• gastrointestinal disease

• chronic and/or psychological disease

• food allergy

• Vegetarian or vegan diets, or other special diets

Related Conditions & MeSH terms

• Healthy Subjects

Intervention

Other:
• High beta glucans
higher dose betaglucans
• Low beta glucans
lower dose beta glucans
• Low beta glucans + low polar lipids
low dose betaglucans in a combination with low dose of polar lipids
• Polar lipids
low dose polar lipids
• Control
No beta glucans or polar lipids

Locations

Country	Name	City	State
Sweden	Lund University, Food Technology, Engineering and Nutrition	Lund

Sponsors (1)

Lead Sponsor	Collaborator
Lund University

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Glucose tolerance	Postprandial glucose concentrations (mmol/L). The incremental area under the curve will be calculated and expressed as mmol*minutes/litre.	3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes
Secondary	Subjective appetite variables	Postprandial sensation of hunger, satiety, and desire to eat will be determined with a 100 millimeter visual analogue scale (VAS). The left end of the VAS scale represent "not at all" (e.g. hungry) and right end of the scale represented "extremely". One scale for each parameter will be used. The total area under the curve will be calculated, and the results will be expressed as millimeter*minutes.	3 hours. Fasting (time =0 minutes), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes