Healthy Subjects Clinical Trial
Official title:
The Link Between Mental Imagery and the Reduction of Fear in Imaginal Extinction
Imaginal exposure is a widely used psychological treatment technique. Imaginal extinction is an experimental analogue of imaginal exposure, that allows the study of this treatment technique under controlled circumstances (Agren, Björkstrand, & Fredrikson, 2017). During imaginal extinction, experimentally induced fear is diminished through repeated exposure to mental imagery of the feared (conditioned) stimulus. However, it is not known to what extent fear reduction depends on the mental imagery produced during this procedure. A better understanding of the mechanisms driving the effects of imaginal exposure and the factors moderating fear reduction could have significant clinical utility, by suggesting mechanistically informed ways to improve this treatment.
The study takes part over three consecutive days, with fear conditioning to visual stimuli on
day 1, imaginal extinction on day 2, and a fear reinstatement procedure, again to visual
stimuli, on day 3. Skin conductance is used to measure fear responses.
Participants' are randomized to receive conditioning, extinction and reinstatement with
either complex or simple stimuli. During imaginal extinction, imagery of each experimental
stimulus is prompted through different verbal instructions.
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