Interval Training in Young Healthy Individuals

Healthy Subjects Clinical Trial

Official title:

Interval Training: Training, Detraining and Retraining; an Interventional Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00733941
• Other study ID #: 4.2008.1755
• Status: Completed
• Phase: N/A
• First received: August 12, 2008
• Last updated: May 26, 2015
• Start date: September 2008
• Est. completion date: December 2009

Study information

• Verified date: May 2015
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Norwegian Social Science Data ServicesNorway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Description:

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: December 2009
• Est. primary completion date: June 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 27 Years

Eligibility

Inclusion Criteria:

• BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

• Hypertension, diabetes and cardiovascular disease.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Exercise Test
• Healthy Subjects

Intervention

Behavioral:
• High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
• normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Locations

Country	Name	City	State
Norway	Norwegian University of Science and Technology	Trondheim
Norway	NTNU	Trondheim

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Hatle H, Støbakk PK, Mølmen HE, Brønstad E, Tjønna AE, Steinshamn S, Skogvoll E, Wisløff U, Ingul CB, Rognmo Ø. Effect of 24 sessions of high-intensity aerobic interval training carried out at either high or moderate frequency, a randomized trial. PLoS On — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxygen uptake		Before and after the training-, detraining- and retraining-phase	No
Secondary	Cardiac function and skeletal muscle enzyme activity		After training, detraining and retraining	No