Healthy Subjects Clinical Trial
Official title:
The Effect of Acute HMG-CoA-Reductase Inhibition (Atorvastatin) on Renal Sodium Excretion, Renal Hemodynamics, Tubular Function and Vasoactive Hormones in Healthy Subjects During Normal and High Sodium Intake
We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium handling, renal hemodynamics, tubular function and vasoactive hormones in healthy humans during normal and high sodium intake.
We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium
handling, renal hemodynamics, tubular function and vasoactive hormones in healthy humans
during normal and high sodium intake.
We wanted to analyze if changes in renal hemodynamics, tubular function, hormones, blood
pressure and HR under acute treatment with atorvastatin depends on sodium intake.
;
Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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