View clinical trials related to Healthy Subjects.
Filter by:A single dose pharmacokinetic study investigating two paracetamol formulations
This study will evaluate the pharmacokinetic profiles of experimental formulations of paracetamol.
The effects of Lacosamide, an antiepileptic drug, on sleep have not been formally evaluated. The present study is being conducted to assess the effects of Lacosamide on sleep quality in healthy subjects.
The objective of the study is to evaluate the pharmacokinetics of lovastatin and lovastatin acid of four 600 mg LipoCol Forte capsules compared to that of one 20 mg lovastatin Tablet after single oral administration in healthy subjects.
Background: - People with motor neuron disorders have changes in the parts of the brain that control movement. Some tests that are currently used to study these changes are magnetic resonance imaging (MRI) and transcranial magnetic stimulation (TMS). We don t know if MRI scans and TMS give the same results if done at different times in the same person. Researchers want to see if these tests produce different results if given to healthy adults on two separate occasions. Objectives: - To test the reliability of different tests of the brain used to study motor neuron disorders. Eligibility: - <TAB>Healthy individuals at least 35 years of age who have no history of neurological disorders and take no medications. - <TAB>Pregnant women may not participate. Design: - Participants will be screened with a medical history and physical exam. - Participants will have two testing visits 1 to 6 months apart. - The first visit will have three parts. The first part is a neurological exam to test strength, sensation, reflexes, and coordination of movement. The second part will be TMS tests. The third part will involve an MRI scan to study the parts of the brain that control movement. - At the second visit, participants will have MRI scanning only.
To compare the pharmacokinetic (PK) profile of TR-700 in elderly subjects versus younger control subjects
This study evaluated the safety & tolerability of two Breathe Right nasal strip prototypes. Prototypes were produced as an improvement to the currently marketed product.
This is a human pharmacology, single-dose study to investigate the pharmacokinetics of orally administered Levetiracetam (LEV) in Japanese subjects with normal renal function and in Japanese subjects with various degrees of impaired renal function.
The study aims to compare blood pressure and pulse in male healthy subjects taking mirabegron and tamsulosin both alone and in combination.
The purpose of this study is to evaluate the effect of EVP-6124 at therapeutic and supratherapeutic concentrations on cardiac repolarization in healthy subjects.