Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population

Healthy Population Clinical Trial

— CoFiKSa  

Official title:

Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population: Response and Adaptation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03509818
• Other study ID #: Ref 47/764390.09/17
• Status: Completed
• Phase: N/A
• Start date: March 21, 2018
• Est. completion date: March 26, 2019

Study information

• Verified date: July 2019
• Source: Universidad Europea de Madrid
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Exercise program in serum Klotho levels

Description:

This study aims to analiyze the effects of acute exercise in serum Klotho levels attending physical fitness in healthy population

Recruitment information / eligibility

• Status: Completed
• Enrollment: 85
• Est. completion date: March 26, 2019
• Est. primary completion date: October 30, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• healthy people between 20 and 45 years old

Exclusion Criteria:

• acute and chronic disease, people who take medication and supplements, smoker.

Related Conditions & MeSH terms

• Healthy Population

Intervention

Other:
• plyometric exercise
acute plyometric exercise
• Aerobic exercise
acute aerobic exercise

Locations

Country	Name	City	State
Spain	Escuela de Doctorado e Invesitgacion, Universidad Europea	Madrid	Villaviciosa De Odon

Sponsors (1)

Lead Sponsor	Collaborator
Universidad Europea de Madrid

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in serum Klotho levels	Change from baseline to acute exercise session	Baseline and one hour
Secondary	Change in Cardiorespiratory Fitness VO2max	For this Variable All people Will perform a exercise test on treadmill (Tecnhogym run race 1400HC; Gambettola, Italy), in this way we determinate the VO2max. Through the modifies Balke protocol. The gas Exchange data Will measured breath by breath using open circuit spirometry and specific face mask for Fitmate, Cosmed; Vmax 29C, Sensormedics machine.	Baseline
Secondary	Change in Body Composition	The age in years; height in centimeters (tallimeter Ano Sayol SL, Barcelona, Spain); weight in kilograms (Inbody 720, Microcaya) and we can derive from this data the variable of Body Mass Index (BMI) calculated as weight (kg)/height (m2).	Baseline
Secondary	Change in Body Composition, Body muscle mass Index	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)	Baseline
Secondary	Change in Body Composition, % of Fat Mass	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)	Baseline
Secondary	Change in Body Composition, Total Muscle Mass	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)	Baseline
Secondary	Change in Body Composition, Visceral Fat Index.	For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA). This value is really important to determine a cardiovascular risk.	Baseline