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Clinical Trial Summary

Bioequivalence study to evaluate the pharmacokinetics of a new crizotinib encapsulated microsphere (eMS) formulation

Clinical Trial Description

In order to overcome the poor taste/palatability associated with the original oral solution formulation of crizotinib for pediatric patients, an encapsulated microsphere (eMS) formulation with improved palatability compared with the oral solution and acceptable PK characteristics was developed. The primary objective of this study is to establish the bioequivalence of the eMS formulation to the current commercial formulation, ie, formulated capsule (FC), in adult healthy participants to support the commercialization of this new formulation. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT04856293
Study type Interventional
Source Pfizer
Contact Pfizer Call Center
Phone 1-800-718-1021
Email [email protected]
Status Recruiting
Phase Phase 1
Start date April 16, 2021
Completion date October 6, 2021

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