Healthy Participants Clinical Trial
The scientific goal of this experiment is to evaluate the performances of our three-dimensional digital model by comparing its prediction computed from underwater data to posture observed during real weightlessness during parabolic flight.
Investigations description Throughout the experiment test subject will be safely attached to
a fixation mechanism at its center of gravity (hip). This mechanism comprises a climbing
harness connected to two lateral vertical guides by two magnetic connection plates at the
level of the hips. The test subject will lie down on the floor on a plate equipped with foam
pads to create a comfortable lying surface. This mechanism allows free postural movement in
microgravity phase and also supports the test subject´s lying position during 1,8g- phase.
At any stage of the experiment the test subject will be able to exit the fixation alone, by
using one hand only.
The harness can be moved vertically by a linear sliding system and springs in the vertical
guides. Springs will remain compressed during the 1g/2g-phase and lift the subject with the
reduction to microgravity.
At the beginning of the weightlessness phase of each parabola, the sliding system will push
participant's body up to about 30cm above the floor. After he has reached the free floating
position, he will be asked to perform a short effort (crouching or stretching) and then to
relax and stay still.
Once free floating, three video cameras with wide angle lenses will record body movements
from front, side and top view. By electronically synchronizing the cameras the produced
images can be used for three-dimensional analysis. Additionally three-dimensional force
sensors at the hip fixation will be used to evaluate the quality of microgravity provided
during the parabolic flight.
Experimental protocol Before flight subjects will be familiarized with the setup and the
protocol. For each flight day, 3 subjects will be studied. The procedure will be the same
for the 3 subjects and on all 3 days.
The subject rests calm at the bottom until microgravity phase starts. As described above a
spring forced linear sliding system will push his body mass up to about 300mm. After the
test subject has reached its free floating position without any contact to the surrounding
area (bottom), he will perform a short effort (crouching or stretching). From now on the
subject should relax and is not allowed to move his muscles intentionally. At the end of
microgravity phase, the sliding system will allow a soft landing on the foam pads.
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Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
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