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Healthy Participants clinical trials

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NCT ID: NCT05577624 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants

Start date: November 5, 2019
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the pharmacokinetic (PK) profile of AMG 510 alone and in combination with rifampin in healthy participants.

NCT ID: NCT05571163 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants

Start date: March 6, 2020
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the pharmacokinetics (PK) of AMG 510 administered as 8 x 120-mg tablets and as water dispersion in healthy participants.

NCT ID: NCT05568082 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Drug-drug Interaction Effect of Itraconazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants

Start date: December 3, 2019
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the pharmacokinetic (PK) profile of AMG 510 administered alone and in combination with itraconazole in healthy participants.

NCT ID: NCT05567510 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Metabolism and Excretion of BMS-986369 in Healthy Male Participants

Start date: October 20, 2022
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess mass balance, biotransformation, and excretion of BMS-986369 following study drug administration.

NCT ID: NCT05564208 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Effect of Food on the Level of Circulating Elafibranor in Healthy Participants After Intake of a Single Tablet

Start date: October 27, 2022
Phase: Phase 1
Study type: Interventional

This study will evaluate the effects of food on how much test drug is able to access the circulation and reach the target area (known as bioavailability). The test drug, elafibranor (IPN60190), is in development for the treatment of primary biliary cholangitis (PBC). PBC is a rare, long-term autoimmune disease of the liver. An autoimmune disease occurs when the immune (defence) system treats healthy parts of the body as if they were foreign and attacks them. This study will be in healthy volunteers, so this trial is not to test if the drug helps to improve health.

NCT ID: NCT05546151 Completed - Clinical trials for Healthy Participants

A Study to Assess the Safety and Tolerability of BMS-986322 in Healthy Participants of Japanese Descent

Start date: September 28, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of multiple ascending oral doses of BMS-986322 in healthy participants of Japanese descent.

NCT ID: NCT05539976 Completed - Clinical trials for Healthy Participants

A Taste Assessment of Iberdomide and Mezigdomide in Healthy Participants

Start date: September 30, 2022
Phase:
Study type: Observational

The purpose of this study is to develop taste profiles of iberdomide and mezigdomide drug substances and oral formulation prototypes in order to develop a pediatric oral form of iberdomide and mezigdomide.

NCT ID: NCT05537142 Recruiting - Clinical trials for Healthy Participants

A Study to Assess the Phamacokinetics of BV100 in Participants With Varying Degrees of Hepatic Impairment

Start date: September 2, 2022
Phase: Phase 1
Study type: Interventional

To investigate the pharmacokinetics (PK) of rifabutin in subjects with hepatic impairment after single intravenous (IV) infusion of BV100

NCT ID: NCT05525910 Completed - Clinical trials for Healthy Participants

Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants

Start date: August 31, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to estimate the relative bioavailability of nirmatrelvir/ritonavir of 4 different FDC tablet formulations relative to the commercial tablet formulation under fasted conditions in healthy adult participants.

NCT ID: NCT05519514 Completed - Healthy Subjects Clinical Trials

Bio-Equivalence Study of Budesonide Prolonged-release Tablets 9 Mg In Healthy Human Adult Subjects

Start date: July 12, 2021
Phase: Phase 1
Study type: Interventional

A randomized, open label, single dose, balanced, two treatment, two sequence, four period, fully replicate, cross over bioequivalence study under fasting condition.