Healthy Lifestyle Clinical Trial
Official title:
Screening to Validate and Identify Nutrition-related Biomarkers for Definded Food Groups (Dairy Products, Whole Grain, Processed Meat, Vegetarian Sausage Alternatives)
The Biomarker study will be conducted (i) to establish biomarker profiles that reflect the daily diet and regularly dietary habits, (ii) to complement self-reported dietary habits and (iii) to reduce gaps between self-reported information and real dietary intake. The study aims to assess relationships between defined nutrient intake (four groups: 1. Milk and dairy products, 2. Whole-grain products (rich in soluble fibers), 3. Sausage and processed meat (pork), 4. Meat-free sausage and meat alternatives (based on egg, soy) and resulting biochemical markers in human samples (plasma, serum, 24 h urine). In a next step, we will focus on unraveling the connection of the established diet-related metabolites with biomarkers of health and disease status, with focus on cardiovascular diseases (CVD).
Within the scope of the present study, biomarkers or biomarker profiles are to be identified which reflect the daily diet and eating habits (focus: mixed diet / Western diet, vegetarians, vegans) in order to supplement or complete the information from diet protocols. The chosen study design enables relationships between a defined nutrient intake in the form of a standardized diet over five days (four groups with 40 subjects each; group 1: Milk and dairy products, group 2: Whole grain products (rich in soluble fiber), group 3: Sausage and processed meat (pork), group 4: Meat-free sausage and meat alternatives (based on egg, soy) and the resulting biochemical markers in the human samples (plasma, serum, whole blood, 24-hour urine). In addition, one subgroup (n = 12) consumed a test meal with the study foods on day 6 after the 5-day standardized diet. Before the test meal (time 0) and at intervals of 30, 60, 120, 180 min, blood samples are taken (postprandial profiling) in order to examine the brief increase in nutrients from the study foods in the human samples. The aim of the study is i) to validate already established biomarkers and ii) to identify new biomarkers / patterns. In the further course of the study, the identified and validated nutrition-associated biomarkers are to be linked to parameters of the health and disease status, whereby in particular the connection to cardiovascular risk factors and endpoints is considered. Furthermore, the study design enables an assessment of the physiological effects as a result of an increased intake of the selected food (groups). ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05109026 -
Connect-5 Needs Assessment Survey to Identify Healthy Lifestyle Requirements of a Rural Irish Community
|
||
Completed |
NCT05510297 -
Active Seating System to Lessen Sedentariness in Older Adults: In-home Testing Phase
|
N/A | |
Completed |
NCT05483296 -
Effects of Afternoon and Evening Light on Teenagers' Melatonin Levels, Alertness, Sleepiness and Sleep
|
N/A | |
Not yet recruiting |
NCT05218980 -
Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health
|
N/A | |
Completed |
NCT04555746 -
Active Kindergarten - Active Children
|
N/A | |
Completed |
NCT01579708 -
Evaluation of the Program SI! for Preschool Education: A School-Based Randomized Controlled Trial
|
Phase 3 | |
Completed |
NCT05273086 -
The Effect of a Sleep Intervention on Sleep Quality in Nursing Students
|
N/A | |
Recruiting |
NCT06022185 -
E-Health Literacy, Digital Literacy, Healthy Lifestyle and Web Based Education for Young Old Individuals
|
N/A | |
Not yet recruiting |
NCT06025019 -
Effectiveness of Parent-based Electronic Health (eHealth) Intervention on Preschoolers' Physical Activity, Dietary Behaviors, and Sleep Problems
|
N/A | |
Completed |
NCT05492162 -
An Intervention to Promote Health Students' Well-being
|
N/A | |
Not yet recruiting |
NCT05031377 -
Effects of Cardiovascular Health Education Program on Community-dwelling Older Adults at Risk of ASCVD
|
N/A | |
Completed |
NCT05002049 -
Science Engagement to Empower Disadvantaged adoleScents (SEEDS Project)
|
N/A | |
Active, not recruiting |
NCT05100953 -
Application of Physical Activity Counseling Program
|
N/A | |
Completed |
NCT04675658 -
Stay Active Physical Activity Program
|
N/A | |
Recruiting |
NCT04571775 -
Effects of a Lifestyle Product on Physiological Measures and Subjective Well-being in Humans: A Systematic Study
|
N/A | |
Recruiting |
NCT05891977 -
Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults
|
N/A | |
Active, not recruiting |
NCT05067816 -
Med-South Lifestyle Program Implementation Study
|
N/A | |
Enrolling by invitation |
NCT05974826 -
Healthy Communities: A Healthy City Preventive Program on Cardiovascular Health and Well-being (HC)
|
N/A | |
Recruiting |
NCT05653258 -
Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
|
Phase 2/Phase 3 | |
Recruiting |
NCT05858593 -
Positive Youth Development in the Metaverse
|
N/A |