Clinical Trials Logo
  1. Home
  2. Healthy Individuals
  3. NCT04941196

Bioequivalence Study of Anplag® 90mg (Ticagrelor) Tablet & Brilinta® 90 mg (Ticagrelor) Tablet in Healthy Adult Male Pakistani Subjects Under Fasting Condition — BE  

Healthy Individuals Clinical Trial

Official title:
A Single Centre, Cross-over, Single Dose, Two Period, Randomized, Open Label Bioequivalence Study of Anplag® 90mg (Ticagrelor) Tablet With Brilinta® 90 mg (Ticagrelor) Tablet in Healthy Adult Male Pakistani Subjects Under Fasting Condition

Clinical Trial Summary

Single oral administration of study drugs (i.e. Anplag® & Brilinta®) in Two periods after at least 10 hours fasting. The periods will be separated by a washout period of 7 days. The purpose of this study is to compare the bioavailability of Anplag® 90mg (Ticagrelor) Tablet with Brilinta® 90 mg (Ticagrelor) Tablet under fasting conditions in healthy Pakistani male subjects.

Clinical Trial Description

The subjects will be randomly assigned in period 1 to T or R sequence and will be administered the study drugs T (Anplag® 90 mg) or R (Brilinta® 90 mg) with 240 mL ambient temperature water following at least 10 hours fasting. Blood samples will be withdrawn at pre-determined time points for estimation of plasma drug concentration upto 48 hours post dose. the subjects will be crossed over in Period 2 separated by a washout period of 7 days and administered RT sequence in period 2. Similar procedure of blood sampling will be applied for estimation of plasma drug concentration upto 48 hours post dose. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04941196
Study type Interventional
Source University of Karachi
Contact
Status Completed
Phase Phase 1
Start date October 16, 2020
Completion date November 25, 2020
View Details
See also
  Status Clinical Trial Phase
Completed NCT06044896 - Physiology of Body Lateralization on Regional Lung Ventilation Study N/A
Completed NCT02101801 - Urine Drug Levels Related to Source of Water for Irrigation for Vegetable Crops Among Healthy Israeli Volunteers N/A
Recruiting NCT06101641 - Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals N/A
Completed NCT03065283 - Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women N/A
Recruiting NCT01721811 - Retinal Function in Relation to Transient or Chronic Challenges to Retinal Metabolism N/A
Completed NCT01211717 - The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients N/A
Completed NCT01568541 - Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes N/A
Completed NCT05541094 - Study of Vitamin D Fortification of Milk and Oil
Completed NCT05597657 - Normal Variation of T1 Values With Cardiac Magnetic Resonance in Healthy Individuals N/A
Completed NCT03728868 - Tolerability and Risk of Adverse Events With a Probiotic Supplement N/A
Recruiting NCT04513782 - The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss
Completed NCT05637060 - Bioequivalence Study of Rosuvastatin Tablet N/A
Not yet recruiting NCT05110885 - Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices
Completed NCT01134978 - Neural Mechanisms of the Contextual Interference Effect: A fNIRs and EEG Study Phase 1
Completed NCT06137534 - Upper Extremity Pattern Exercises and Respiratory Functions N/A
Completed NCT04873570 - Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistani Subjects Phase 1
Enrolling by invitation NCT01872091 - Analysis of Neuromuscular, Circulatory and Biomechanical Responses After Cryotherapy N/A
Completed NCT01872117 - Assessment of Temperature by Infrared Thermography and Blood Conduction Velocity by Doppler After Applying Shortwave Diathermy and Microwave - Correlations With Cardiovascular and Hemodynamic Parameters N/A
Completed NCT02409836 - A Study to Assess the Ingestion of Dentifrice by Children N/A
Recruiting NCT05358561 - Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals N/A