Study the Effect of Water Kefir Consumption on the Gut Microbiome in Healthy Adults

Healthy Diet Clinical Trial

Official title:

Analysis of the Intestinal Flora Composition After Consumption of Water Kefir

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05657730
• Other study ID #: Water Kefir
• Status: Recruiting
• Phase: N/A
• Start date: November 10, 2022
• Est. completion date: April 14, 2023

Study information

• Verified date: December 2022
• Source: Lund University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this intervention study is to analyse the microbiota composition after the water kefir consumption. The main questions are to evaluate the potential probiotic drink can have beneficial effect on the gut microbiota. Participants will consume the water kefir for two weeks and microbiota will be analysed. Researchers will compare the microbiota composition before and after consumption.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 63
• Est. completion date: April 14, 2023
• Est. primary completion date: January 14, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18-65 years of age.

• must be able to complete the form digitally.

Exclusion Criteria:

• must not be diagnosed with gastrointestinal diseases, autoimmune diseases or have diseases or medications that cause immune deficiency such as MS, type 1 diabetes, cancer or HIV.

• must not take antibiotics during the study period.

Related Conditions & MeSH terms

• Gastrointestinal Microbiome
• Healthy Diet
• Probiotics

Intervention

Dietary Supplement:
• Water Kefir beverage
Participants will consume the water kefir beverage for two weeks.

Locations

Country	Name	City	State
Sweden	Lund University	Lund	Skåne

Sponsors (1)

Lead Sponsor	Collaborator
Lund University

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	16S metagenomics based measurement of the bacterial diversity (alpha- and beta diversity indices), and the composition (relative abundance of the bacterial taxa in each sample)	Potential changes of microbiome after consumption of the water kefir will be assessed by analyzing the 16S metagenomics	up to 24 weeks