Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Healthy Controls Clinical Trial

Official title: Visceral Sensitivity in IBD and IBS: Role of Inflammation, Immune Activity and Genetic Factors

Status Recruiting

Clinical Trial Summary

Aim:

More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.

Clinical Trial Description

Methods:

Sample collection in healthy subjects, IBD and IBS patients:

• biopsy of rectum and colon descendens

• blood sample collection

• collection of sample of nasal mucosa

• feces collection

• questionnaires

• rectal barostat sensitivity measurement

• transit measurement of colon

• MR scan of brain ;

Related Conditions & MeSH terms

• Colitis
• Colitis, Ulcerative
• Crohn Disease
• Crohn's Disease, Active
• Crohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
• Healthy Controls
• IBS
• Ulcer
• Ulcerative Colitis, Active
• Ulcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)

• NCT number: NCT02421705
• Study type: Interventional
• Source: KU Leuven
• Contact: Koen Bellens, MSc
• Phone: 0032-16-341943
• Email: koen.bellens@kuleuven.be
• Status: Recruiting
• Phase: N/A
• Start date: February 2010
• Completion date: January 2099