Healthy Controls Clinical Trial
Official title:
Establishment of Normative Data of Brain Network Activation (BNA) Using Evoked Response Potentials in Adolescents and Young Adults
Establish normative data of ElMindA's Brain Network Activation (BNA) using evoked response in two age groups: adolescents and young adults.
Currently, there is no reliable, practical, and non-invasive method for assessing changes in
electrophysiological activity of the brain associated with brain-related pathologies, e.g.,
concussion, ADHD, autistic spectrum disorders (ASD), etc. Event Related Potentials (ERPs),
which are temporal reflections of the neural mass electrical activity of cells in specific
regions of the brain that occur in response to stimuli, may offer such a method, as they
provide both a noninvasive and portable measure of brain function. The ERPs provide excellent
temporal information, but spatial resolution for ERPs has traditionally been limited.
However, by using high-density electroencephalograph (EEG) recording spatial resolution for
ERPs is improved significantly. The paradigm for the current study will combine
neurophysiological knowledge with mathematical signal processing and pattern recognition
methods (BNA) to temporally and spatially map brain function, connectivity and
synchronization.
The need of objective measures that will help the clinician in its decision making in
brain-related pathologies is recognized. BNA is a new imaging modality that has been
developed to fill this gap.
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