The Brain Processes Underlying Speech Motor Learning and Speech Production

Healthy Adults Clinical Trial

Official title:

Improving Speech Motor Learning Processes Using Augmented Behavioral Interventions

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05918679
• Other study ID #: STUDY00017657
• Secondary ID: R01DC019905
• Status: Recruiting
• Phase: N/A
• Start date: June 1, 2023
• Est. completion date: August 2026

Study information

• Verified date: July 2023
• Source: Arizona State University
• Contact: Ayoub Daliri
• Phone: 4807278397
• Email: ayoub.daliri[@]asu.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this research is to develop protocols that selectively target and improve speech-motor learning processes. Participants will be asked to name pictures, read words/sentences, and listen to sounds while their speech signals will be collected during the study.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 510
• Est. completion date: August 2026
• Est. primary completion date: August 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years and older
• native speaker of American English
• normal (age-appropriate) binaural pure-tone hearing threshold
• not taking medications affecting sensorimotor functioning
• no current or history of communication, neurological, or psychological disorders Exclusion Criteria:

Related Conditions & MeSH terms

• Healthy Adults

Intervention

Behavioral:
• Effects of speech variability on speech motor learning
This intervention will examine whether reducing normal variability of speech could improve error detection and speech motor learning. We will design training tasks to change subjects' speech variability. We will train subjects to decrease/decrease their speech variability. Upon completing the training tasks, subjects will complete a motor learning task.
• Effects of error-detection training on speech motor learning
This intervention will examine whether improving subjects' ability to detect and estimate auditory perturbation could improve speech motor learning. For this purpose, we will design training tasks to change subjects' estimation of the perturbation magnitude. After completing the training tasks, subjects will complete the motor learning task.
• Contributions of error awareness to speech motor learning
This intervention will examine the contributions of error awareness to speech motor learning. Subjects will produce a target word while receiving perturbed auditory feedback with different magnitudes. Subjects will be trained to indicate the magnitude of the error they perceived with or without visual feedback.
• Enhancing auditory-to-motor mapping with augmented visual feedback
This intervention will determine the contributions of enhanced auditory-to-motor mappings to speech motor learning. We will design training tasks in which we will use visual feedback to provide feedback regarding subjects' accuracy of auditory-to-motor mapping.
• Effects of enhanced auditory-motor awareness on speech motor learning
In this intervention, subjects will be trained to control their articulators more accurately and be more aware of their articulators' position and their auditory consequences. After the training tasks, subjects will complete a motor learning task.

Locations

Country	Name	City	State
United States	Arizona State University	Tempe	Arizona

Sponsors (2)

Lead Sponsor	Collaborator
Arizona State University	National Institute on Deafness and Other Communication Disorders (NIDCD)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in speech output in response to previously experienced auditory errors	In each trial, participants will experience an auditory error while they produce speech (e.g., they may say "head" but hear "had"). Participants' speech will be measured in each trial. The investigators will measure how the participants' speech changes due to auditory errors experienced in previous trials.	within each session of the study that may last up to 2 hours
Primary	Change In Speech Output Immidiately After Hearing Auditory Errors	In each trial, participants will experience an auditory error while they produce speech (e.g., they may say "head" but hear "had"). The investigators will measure how the participants' speech changes due to auditory errors that they experience in the current trial.	within each session of the study that may last up to 2 hours