Aspirin Effects on Emotional Reactions

Status Completed

Clinical Trial Summary

The aim of this study is to determine whether the drug aspirin has effects on emotional reactivity, emotional memory, and risk-taking behaviors.

Clinical Trial Description

The goal of this study is to determine if aspirin (acetylsalicylic acid) alters emotional reactions to emotion evoking pictures as well as memory for them. Using a double-blind parallel arm study, participants will receive either placebo or a pain-relieving dose of aspirin (500mg). One hour later they will complete 30 minutes of tasks. This will include ratings of emotional pictures and memory for them. The paradigm is similar to previous experiments done in this lab using other cyclooxygenase inhibitors: ibuprofen and acetaminophen (Durso, Luttrell, & Way, 2015; Psychological Science, https://doi.org/10.1177/0956797615570366). Risk taking on the Balloon Analogue Risk Task will also be assessed. Participants will be healthy young adult males at Ohio State University. ;

Study Design

Related Conditions & MeSH terms

Healthy Adults

Clinical Trial Details

NCT number	NCT04146532
Study type	Interventional
Source	Ohio State University
Contact
Status	Completed
Phase	Early Phase 1
Start date	October 8, 2019
Completion date	April 15, 2022

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