Investigating Memory Retrieval Improvement in Healthy Subjects

Healthy Adults Clinical Trial

Official title:

Investigating Memory Retrieval Improvement in Healthy Subjects

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03312920
• Other study ID #: 17-132
• Status: Active, not recruiting
• Phase: N/A
• Start date: September 27, 2017
• Est. completion date: September 5, 2024

Study information

• Verified date: October 2023
• Source: The University of Texas at Dallas
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

Description:

Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.

Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether learning can be accelerated and associative memory improved by using tDCS, this study will compare the performance in a Face Name Associate memory task from 3 groups. The first group will get active aodal tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task and the third group will get active cathodal tDCS.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 56
• Est. completion date: September 5, 2024
• Est. primary completion date: October 6, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Age: 18-35 years Native English Speaker

Exclusion Criteria:

• History of severe head injuries, epileptic insults, or heart disease. Severe psychiatric disorders and severe untreated medical problems. Contraindications for tDCS (pregnant women, implanted devices)

Related Conditions & MeSH terms

• Healthy Adults

Intervention

Device:
• active anodal tDCS
active anodal tDCS with memory task
• sham tDCS
sham tDCS with memory task
• active cathodal tDCS
active cathodal tDCS with memory task

Locations

Country	Name	City	State
United States	University of Texas at Dallas	Richardson	Texas

Sponsors (1)

Lead Sponsor	Collaborator
The University of Texas at Dallas

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Associative Memory assessed by a Face Name Associate Memory experiment	Changes in performance in the Face Name Associate memory task is compared between the 2 groups (1. Real tDCS+ Face Name Associate memory task & 2. Sham tDCS+ Face Name Associate memory task) to investigate the influence of tDCS on Associative Memory.	Associate Memory is assessed after a 10 minutes break following the study phase