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Healthy Adult Subjects clinical trials

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NCT ID: NCT04811469 Completed - Clinical trials for Healthy Adult Subjects

Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults

Start date: May 24, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of CBP-174 after a single oral dose in healthy adult subjects.

NCT ID: NCT04783766 Completed - Clinical trials for Healthy Adult Subjects

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Start date: April 10, 2021
Phase: Phase 1
Study type: Interventional

The purposes of this study are to: 1. Learn about the safety of CK-3773274 after a single dose and multiple doses in Chinese healthy adult subjects. 2. Learn how healthy subjects tolerate CK-3773274 after a single dose and multiple doses. 3. Find out how much CK-3773274 is in the blood after a single dose and multiple doses. 4. Determine the effect of doses of CK-3773274 on the pumping function of the heart. 5. Evaluate the effect CYP2D6 genetic polymorphisms on how the body metabolizes CK-3773274.

NCT ID: NCT04776135 Completed - Clinical trials for Healthy Adult Subjects

Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric Tube

Start date: February 26, 2021
Phase: Phase 1
Study type: Interventional

To investigate the comparative bioavailability of edaravone oral suspension administered orally and via a nasogastric tube in healthy adult subjects

NCT ID: NCT04629131 Completed - Clinical trials for Healthy Adult Subjects

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Healthy Adults

Start date: November 25, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics properties of TNM002 following a single intramuscular dose in healthy adult subjects.

NCT ID: NCT04627129 Completed - Clinical trials for Healthy Adult Subjects

A Itraconazole Effect Study of SHR2554 on Healthy Chinese Adult Subjects

Start date: June 1, 2020
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the effect of Itraconazole on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR2554 tablets. The secondary objective of the study is to evaluate the safety of single dose of SHR2554 orally in healthy subjects.

NCT ID: NCT04596605 Completed - Clinical trials for Healthy Adult Subjects

Gastrointestinal Tolerance Assessment of T2309

GATA
Start date: July 15, 2020
Phase: N/A
Study type: Interventional

Gastrointestinal Tolerance assessment of T2309 compared to a food supplement in 50 subjects.

NCT ID: NCT04586985 Completed - Sickle Cell Disease Clinical Trials

Safety, Tolerability and Pharmacokinetics of FTX-6058

Start date: October 26, 2020
Phase: Phase 1
Study type: Interventional

This is a study to evaluate the safety, tolerability and pharmacokinetics of FTX-6058 in healthy adult subjects and adult subjects with sickle cell disease (SCD).

NCT ID: NCT04521192 Completed - Clinical trials for Healthy Adult Subjects

Bioequivalence of Fluzoparib(SHR3162) Study on Healthy Chinese Adult Subjects

Start date: May 6, 2019
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the bioequivalence of two different specification of reference preparation capsules (10 mg/capsule, 40 mg/capsule and 100 mg/capsule, 1 capsule each) and test preparations capsules (50 mg/capsule×3). Two different specifications of fluzoparib was provided by Jiangsu HengRui Pharmaceutical Co., Ltd. The secondary objective of the study is to evaluate the safety of test preparations and reference preparation fluzoparib capsules of different specifications in healthy subjects.

NCT ID: NCT04494659 Completed - Clinical trials for Healthy Adult Subjects

A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib

Start date: July 20, 2020
Phase: Phase 1
Study type: Interventional

The primary objective of the study was to assess the effect of repeated oral doses of Rifampicin on the pharmacokinetic profile of a single dose of Famitinib. The secondary objective of the study was to assess the safety of Famitinib given alone versus Famitinib co-administered with Rifampicin.

NCT ID: NCT04493281 Completed - Clinical trials for Healthy Adult Subjects

Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects

Start date: March 22, 2019
Phase: Phase 1
Study type: Interventional

To evaluate the single-dose bioequivalence of oral suspension and intravenous (IV) formulation of edaravone in the fasting state in healthy adult subjects