Healthy Adult Males Clinical Trial
Official title:
Application of Indicator Amino Acid Oxidation Technique to Determine Non-essential Amino Acids/Nitrogen Requirements in Adult Humans
Verified date | July 2017 |
Source | University of British Columbia |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Protein is a major structural component of all cells in the body. The nutritional importance
of protein is because of their amino acids. 9 are called essential and 11 are called
non-essential, based on whether we need to get them from diet. This classification is based
on studies done using older techniques. Recent studies suggest that these so called
non-essential amino acids play important roles in our body's health. For the first time, this
proposal defines an experimental design to examine non- essential amino acid/nitrogen
requirements and metabolism in humans using the Indicator Amino Acid Oxidation (IAAO)
technique.
The objective of the current study is to examine the application of IAAO technique to
determine the non-essential amino acid/nitrogen requirement in adult humans.
Status | Completed |
Enrollment | 6 |
Est. completion date | April 2015 |
Est. primary completion date | January 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: - 20-40 years of age - Male - Classified as normal body weight based on body mass index (BMI) 18.5-25kg/m2 - Free of any concurrent illness Exclusion Criteria: - Men not in good health or have a metabolic, neurological, genetic or immune disorder including diabetes and hypertension - Men who are classified as underweight(<18.5kg/m2), overweight(25-30kg/m2) or obese (>30kg/m2) using the BMI classification) - Men who are allergic to milk, eggs and egg protein |
Country | Name | City | State |
---|---|---|---|
Canada | Child and Family Research Institute | Vancouver | British Columbia |
Lead Sponsor | Collaborator |
---|---|
University of British Columbia | Ajinomoto Co., Inc. |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 13 Carbon dioxide production | Urine and breath samples will be collected to measure the rate of oxidation of expired breath and flux by enrichment of urine. | 8 hours (1study day) |
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