Apigenin in Increasing Health Benefits in High Risk Breast Clinic Patients

Status Withdrawn

Clinical Trial Summary

This pilot clinical trial studies the side effects and best dose of apigenin in increasing health benefits in high risk breast clinic patients. Celery is high in apigenin, a compound that may have anti-cancer activities. Eating a celery-based diet may help in prevention and treatment of inflammatory diseases including cancer.

Clinical Trial Description

PRIMARY OBJECTIVES; I. To determine the feasibility of apigenin oral supplementation using a specially formulated celery-banana bread. II. To determine the safety and tolerability of apigenin supplementation. OUTLINE: This is a dose-escalation study. Patients consume one serving of lower dose apigenin celery-banana bread daily on days 1-7, and then consume one serving of higher dose apigenin celery-banana bread on days 8-14. Patients undergo blood sample collection on day 1 prior to and 6 hours after bread ingestion, on day 8 prior to and 6 hours after ingestion of bread, and on day 15 (or endpoint). Patients also provide a baseline urine sample and then 24-hour urine samples on days 1, 7, 8, and 14. ;

Study Design

Related Conditions & MeSH terms

Health Status Unknown

Clinical Trial Details

NCT number	NCT03139227
Study type	Interventional
Source	Ohio State University Comprehensive Cancer Center
Contact
Status	Withdrawn
Phase	N/A
Start date	August 15, 2017
Completion date	March 14, 2019

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03234556` - Diagnosing Clinically Significant Prostate Cancer In African American and White Men With Elevated PSA	N/A
Active, not recruiting	`NCT02194387` - Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members	N/A
Completed	`NCT03725449` - Internet-based Intervention for Skin Self-Examination in Participants With Increased Risk for Melanoma	N/A
Terminated	`NCT02501759` - Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate Cancer	N/A
Completed	`NCT01550783` - Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening	N/A
Terminated	`NCT04179227` - Focus Group in Collecting Feedbacks From Indoor Tanning Bed Users for Social Media-Delivered Intervention Development
Active, not recruiting	`NCT03199209` - Your Health Matters! (Tu Salud ¡Si Cuenta!): Promoting Healthy Lifestyles in Latino Families	N/A
Completed	`NCT00977392` - Self-Sampling in Women Who Do Not Undergo Routine Cervical Screening	N/A
Completed	`NCT00922285` - Art Therapy for Caregivers of Young Patients Undergoing Bone Marrow Transplant for Cancer	N/A
Active, not recruiting	`NCT03441321` - Social-Media Intervention in Reducing Tanning in High-Risk Tanners	N/A
Terminated	`NCT03412370` - Questionnaires and Cognitive Assessments Following Mammography
Completed	`NCT02264782` - PreView: The Preventive Video Education in Waiting Rooms Program	N/A
Active, not recruiting	`NCT03674229` - Patients Navigators in Facilitating Weight Management in Obese Participants	N/A
Completed	`NCT02355262` - CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
Completed	`NCT02677012` - Autologous Fat Grafting Techniques in Patients Undergoing Reconstructive Surgery
Completed	`NCT03115372` - Lay Health Worker Outreach in Increasing Colorectal Cancer Screening in Asian Americans	N/A
Completed	`NCT00897403` - Blood and Tissue Sample Collection for Future Colon Cancer Biomarker Studies in Patients Undergoing Colonoscopy	N/A
Completed	`NCT04069923` - OsteoCrete in Filling Bone Voids in Participants With Bone Voids or Defects	N/A
Terminated	`NCT03688945` - Art in Improving Outcomes in Participants Undergo Surgery	N/A
Withdrawn	`NCT00717535` - Studying Umbilical Cord Blood From African-American Donors	N/A