Pennington Center Longitudinal Study (PCLS)

Health Behaviors Clinical Trial

— PCLS  

Official title:

Pennington Center Longitudinal (PCLS)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00959270
• Other study ID #: PBRC 28027
• Status: Recruiting
• Start date: May 2009
• Est. completion date: February 2025

Study information

• Verified date: July 2023
• Source: Pennington Biomedical Research Center
• Contact: Peter Katzmarzyk, PhD
• Phone: 225-763-2563
• Email: doctors[@]pbrc.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to develop a cohort of volunteers that can be studied and followed up into the future for changes in health behaviors and development of health problems.

Description:

The PCLS represents an effort to utilize the data collected over the last twenty years during the clinical research studies conducted at Pennington Biomedical Research Center. A cohort will be developed and used for cross-sectional analyses, as well as followed prospectively for the development of a variety of health-related outcomes. Several data sources from the PBRC clinical database will be used to establish the PCLS database, including screening, archive and study-specific data. The only protocol specific to the PCLS study is the collection of blood sample for risk factor determination and storage in the PBRC archive bank, only to be invoked in cases where studies do not include a blood draw as part of their protocol.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30000
• Est. completion date: February 2025
• Est. primary completion date: February 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years or older
• volunteer to Participate

Exclusion Criteria:

• younger than 18 years
• Pregnant

Related Conditions & MeSH terms

• Development of Health Problems
• Health Behaviors

Locations

Country	Name	City	State
United States	Pennington Biomedical Research Center	Baton Rouge	Louisiana

Sponsors (1)

Lead Sponsor	Collaborator
Pennington Biomedical Research Center

Country where clinical trial is conducted

United States, 

References & Publications (23)

Barreira TV, Harrington DM, Staiano AE, Heymsfield SB, Katzmarzyk PT. Body adiposity index, body mass index, and body fat in white and black adults. JAMA. 2011 Aug 24;306(8):828-30. doi: 10.1001/jama.2011.1189. No abstract available. — View Citation

Barreira TV, Staiano AE, Harrington DM, Heymsfield SB, Smith SR, Bouchard C, Katzmarzyk PT. Anthropometric correlates of total body fat, abdominal adiposity, and cardiovascular disease risk factors in a biracial sample of men and women. Mayo Clin Proc. 20 — View Citation

Brown JC, Yang S, Mire EF, Wu X, Miele L, Ochoa A, Zabaleta J, Katzmarzyk PT. Obesity and cancer death in white and black adults: A prospective cohort study. Obesity (Silver Spring). 2021 Dec;29(12):2119-2125. doi: 10.1002/oby.23290. Epub 2021 Oct 24. — View Citation

Brown JC, Yang S, Mire EF, Wu X, Miele L, Ochoa A, Zabaleta J, Katzmarzyk PT. Obesity and Cancer Risk in White and Black Adults: A Prospective Cohort Study. Obesity (Silver Spring). 2021 Jun;29(6):960-965. doi: 10.1002/oby.23163. — View Citation

Broyles ST, Bouchard C, Bray GA, Greenway FL, Johnson WD, Newton RL, Ravussin E, Ryan DH, Smith SR, Katzmarzyk PT. Consistency of fat mass--fat-free mass relationship across ethnicity and sex groups. Br J Nutr. 2011 Apr;105(8):1272-6. doi: 10.1017/S000711 — View Citation

Camhi SM, Bray GA, Bouchard C, Greenway FL, Johnson WD, Newton RL, Ravussin E, Ryan DH, Smith SR, Katzmarzyk PT. The relationship of waist circumference and BMI to visceral, subcutaneous, and total body fat: sex and race differences. Obesity (Silver Sprin — View Citation

Camhi SM, Katzmarzyk PT. Differences in body composition between metabolically healthy obese and metabolically abnormal obese adults. Int J Obes (Lond). 2014 Aug;38(8):1142-5. doi: 10.1038/ijo.2013.208. Epub 2013 Nov 12. — View Citation

Camhi SM, Katzmarzyk PT. Total and femoral neck bone mineral density and physical activity in a sample of men and women. Appl Physiol Nutr Metab. 2012 Oct;37(5):947-54. doi: 10.1139/h2012-075. Epub 2012 Jul 23. — View Citation

Hu G, Bouchard C, Bray GA, Greenway FL, Johnson WD, Newton RL Jr, Ravussin E, Ryan DH, Katzmarzyk PT. Trunk versus extremity adiposity and cardiometabolic risk factors in white and African American adults. Diabetes Care. 2011 Jun;34(6):1415-8. doi: 10.233 — View Citation

Johnson WD, Bouchard C, Newton RL Jr, Ryan DH, Katzmarzyk PT. Ethnic differences in self-reported and measured obesity. Obesity (Silver Spring). 2009 Mar;17(3):571-7. doi: 10.1038/oby.2008.582. Epub 2008 Dec 18. — View Citation

Katzmarzyk PT, Barreira TV, Harrington DM, Staiano AE, Heymsfield SB, Gimble JM. Relationship between abdominal fat and bone mineral density in white and African American adults. Bone. 2012 Feb;50(2):576-9. doi: 10.1016/j.bone.2011.04.012. Epub 2011 Apr 2 — View Citation

Katzmarzyk PT, Bray GA, Greenway FL, Johnson WD, Newton RL Jr, Ravussin E, Ryan DH, Bouchard C. Ethnic-specific BMI and waist circumference thresholds. Obesity (Silver Spring). 2011 Jun;19(6):1272-8. doi: 10.1038/oby.2010.319. Epub 2011 Jan 6. — View Citation

Katzmarzyk PT, Bray GA, Greenway FL, Johnson WD, Newton RL Jr, Ravussin E, Ryan DH, Smith SR, Bouchard C. Racial differences in abdominal depot-specific adiposity in white and African American adults. Am J Clin Nutr. 2010 Jan;91(1):7-15. doi: 10.3945/ajcn — View Citation

Katzmarzyk PT, Brown JC, Yang S, Mire EF, Wu XC, Miele L, Ochoa AC, Zabaleta J. Association of Abdominal Visceral Adiposity and Total Fat Mass with Cancer Incidence and Mortality in White and Black Adults. Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8 — View Citation

Katzmarzyk PT, Greenway FL, Heymsfield SB, Bouchard C. Clinical utility and reproducibility of visceral adipose tissue measurements derived from dual-energy X-ray absorptiometry in White and African American adults. Obesity (Silver Spring). 2013 Nov;21(11 — View Citation

Katzmarzyk PT, Heymsfield SB, Bouchard C. Clinical utility of visceral adipose tissue for the identification of cardiometabolic risk in white and African American adults. Am J Clin Nutr. 2013 Mar;97(3):480-6. doi: 10.3945/ajcn.112.047787. Epub 2013 Jan 30 — View Citation

Katzmarzyk PT, Hu G, Cefalu WT, Mire E, Bouchard C. The importance of waist circumference and BMI for mortality risk in diabetic adults. Diabetes Care. 2013 Oct;36(10):3128-30. doi: 10.2337/dc13-0219. Epub 2013 Jun 11. — View Citation

Katzmarzyk PT, Mire E, Bouchard C. Abdominal obesity and mortality: The Pennington Center Longitudinal Study. Nutr Diabetes. 2012 Aug 27;2(8):e42. doi: 10.1038/nutd.2012.15. — View Citation

Katzmarzyk PT, Mire E, Bray GA, Greenway FL, Heymsfield SB, Bouchard C. Anthropometric markers of obesity and mortality in white and African American adults: the pennington center longitudinal study. Obesity (Silver Spring). 2013 May;21(5):1070-5. doi: 10 — View Citation

Newton RL Jr, Bouchard C, Bray G, Greenway F, Johnson WD, Ravussin E, Ryan D, Katzmarzyk PT. Abdominal adiposity depots are correlates of adverse cardiometabolic risk factors in Caucasian and African-American adults. Nutr Diabetes. 2011 Jan 31;1(1):e2. do — View Citation

Staiano AE, Bouchard C, Katzmarzyk PT. BMI-specific waist circumference thresholds to discriminate elevated cardiometabolic risk in White and African American adults. Obes Facts. 2013;6(4):317-24. doi: 10.1159/000354712. Epub 2013 Aug 9. — View Citation

Sullivan R, Johnson WD, Katzmarzyk PT. Waist circumference is an independent correlate of errors in self-reported BMI. Obesity (Silver Spring). 2010 Nov;18(11):2237-9. doi: 10.1038/oby.2010.178. Epub 2010 Aug 19. — View Citation

Sung YJ, Perusse L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR Jr, Katzmarzyk P, Curran JE, Jeffrey Carr J, Blangero J, Ghosh S, Despres JP, Rankinen T, Rao DC, Bouchard C. Genome-wide association studies suggest sex-speci — View Citation

* Note: There are 23 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cross-sectional analyses database	The only protocol specific to the PCLS study is the collection of blood sample for risk factor determination and storage in the PBRC archive bank, only to be invoked in cases where studies do not include a blood draw as part of their protocol. The PCLS represents an effort to utilize a data collection over the last twenty years during the clinical research studies for cross-sectional analyses, as well as followed prospectively for the development of a variety of health-related outcomes.	twenty-years