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NCT05679765 Clinical Trial

Efficacy of GONB in Patients of Migraine

Headache Clinical Trial

Official title:
Analgesic Efficacy of Ultrasound-guided Greater Occipital Nerve Block in Patients of Chronic Migraine

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05679765
Other study ID # GONB for migraine
Secondary ID
Status Completed
Phase Phase 4
First received
Last updated
Start date April 1, 2022
Est. completion date August 31, 2022

Study information
Verified date January 2023
Source Pain Medicine Department
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022. Fifty patients suffering from migraine were included in the study. Patients in Group G were given greater occipital nerve block (GONB) with lignocaine and dexamethasone under ultrasound guidance while those in Group S were given saline 0.9% as placebo. Pain score using Numeric Rating Scale and number of headache days was assessed at four,eight and twelve weeks after the procedure as a primary outcome. Total headache days were recorded as a secondary outcome.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date August 31, 2022
Est. primary completion date August 31, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - Patients between 18 to 60 years - diagnosed case of migraine Exclusion Criteria: - Patients with known allergies to local anaesthetics - pregnancy - history of cranial or cervical surgery - head injury - headaches secondary to medication overuse - patients with uncontrolled systemic disease like blood pressure, diabetes mellitus - hypo or hyperthyroidism - patient who had already received GONB or botulinum toxin type A therapy within last 6 months - major psychiatric disorder - history of chronic pain syndromes

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Greater Occipital Nerve Block with dexamethasone and lidocaine
Ultrasound guided Greater occipital nerve block on the side of headache
• Greater Occipital Nerve Block with 0.9% saline
Ultrasound guided Greater occipital nerve block on the side of headache

Locations
Country Name City State
Pakistan Pain Medicine Department Lahore

Sponsors (1)
Lead Sponsor Collaborator
Pain Medicine Department

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Analgesic efficacy Change in Pain score assessed on Numeric Rating Scale (NRS) which ranges from 0 to 10. 0 is no pain and 10 is maximum pain. 12 weeks
Secondary Headache days Number of headache days over the course of study period. 12 weeks
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