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The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers

Headache Clinical Trial

Official title:
The Hemodynamic Effects of CGRP After Glibenclamide Administration in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers

Clinical Trial Summary

To investigate the hemodynamic effects of CGRP after glibenclamide administration.

Clinical Trial Description

20 healthy participants will randomly be allocated to receive CGRP infusion followed by glibenclamide or placebo on two different days.

The aim of the study is to investigate the vascular effect of CGRP after glibenclamide administration.

Repeated measurements covering the arteria radialis (RA), superficiel temporal artery (STA) and middle cerebral artery (MCA) before and after glibenclamide/placebo administration and CGRP infusion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04231617
Study type Interventional
Source Danish Headache Center
Contact
Status Completed
Phase N/A
Start date January 20, 2020
Completion date September 1, 2020
View Details
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