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Olanzapine for Acute Headaches — Olanzapine  

Headache Clinical Trial

Official title:
Oral Rapidly Dissolving Olanzapine for Acute Primary Headache in the Emergency Department Setting: A Feasibility Trial

Clinical Trial Summary

This trial is a prospective, randomized, feasibility trial with the primary aim of comparing how well oral rapidly dissolving olanzapine controls primary headache pain when compared to the current treatment strategies used in emergency departments which often require intravenous or intramuscular medications.

Clinical Trial Description

Primary Question: Does oral rapidly dissolving olanzapine provide efficacious analgesia in patients with acute headache of non-organic origin (primary headache) who come to the ED for abortive therapy when compared to current standard of care? Secondary Aim: Additionally, the study will aim to see if oral rapidly dissolving olanzapine decreases 1) duration of ED length of stay and 2) need for IV access when compared to the current standard of care. This is a prospective, randomized, convenience sample, feasibility trial to test for non-inferiority of oral rapidly dissolving olanzapine versus current emergency department standard of care in providing symptomatic relief to patients presenting with primary headache. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03066622
Study type Interventional
Source HealthPartners Institute
Contact
Status Completed
Phase Phase 4
Start date July 2016
Completion date May 20, 2018
View Details
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