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Headache, Tension clinical trials

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NCT ID: NCT06405646 Enrolling by invitation - Orofacial Pain Clinical Trials

Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin

Start date: June 2024
Phase:
Study type: Observational

The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with chronic pain in the masticatory muscles and from people without this pain. Moreover, study participants will be examined by a qualified doctor, according to the validated and standardized international DC/TMD protocol (Diagnostic Criteria for Temporomandibular Disorders) and the criteria included in ICOP-1 (International Classification of Orofacial Pain, 1st edition). The nature and duration of pain, psychoemotional state and central sensitization (the phenomenon of increased reactivity of the nervous system to stimuli) will be determined using validated questionnaires. The obtained results will be subjected to statistical analysis in order to check the relationships between the examined parameters.

NCT ID: NCT05961501 Not yet recruiting - Headache Clinical Trials

The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin

Start date: July 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to evaluate the effectiveness of an aqueous solution containing CBD and CBN in the management of Facial Pain and Headache of Muscular Origin. A randomized (block randomization), double-blind, two-arm controlled trial will involve 42 adult patients diagnosed with Facial Pain and Headache of Muscular Origin which is lasting more than 3 months on the basis of clinical examination. Qualified study participants will be randomly assigned to two groups. The studied group will receive tan aqueous solution containing CBD and CBN, to drink at home in the dose determined by the attending physician, while the control group will receive an aqueous solution of placebo, to drink at home in the dose determined by the attending physician during this time. Each subject will be tested on the qualification day (D0), on 20 days after D0 (D20), and then 40 (D40) and 60 (D60) days after the qualification day using electromyography (EMG), pressure pain threshold test (PPT), clinical examination and surveys.

NCT ID: NCT04765501 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Impact Questionnaire (HIQ).

NCT ID: NCT04736654 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).

NCT ID: NCT04623203 Recruiting - Children, Only Clinical Trials

The Prognosis of Migraine and Tension-Type Headache in Children and Adolescents

Start date: November 22, 2018
Phase:
Study type: Observational [Patient Registry]

Children and adolescents that visited the pediatric neurology clinic at the Bnai Zion medical center do to migraine or TTH headache between the years 2007-2010 were reevaluated. We used a structured headache questionnaire through a phone interview with the patients and their caregivers. Data regarding demographics, the patients' and families' medical history, and headache history, past and current (age at onset, location, quality, frequency, duration of episodes, aura, associated symptoms and treatment) were collected.