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Head Trauma,Closed clinical trials

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NCT ID: NCT04631484 Recruiting - Head Trauma,Closed Clinical Trials

International Trial of Efficacy of Cytoflavin in Head Trauma

MITRA
Start date: October 8, 2020
Phase: Phase 3
Study type: Interventional

The study will access the efficacy and safety of treatment with CITOFLAVIN® in patients with non-penetrating moderately severe traumatic brain injury (TBI). The study recruits patients 18-60 years with TBI, corresponding to the clinical diagnosis of brain contusion, with GCS score 9 -14 at the time of inclusion , with the estimated time of initiation of therapy within 24 hours from the estimated or established time of trauma, with post-traumatic amnesia, confusion or disorientation and absence of indications for neurosurgery or other surgical intervention under general anesthesia. Cytoflavin® (Inosine + Nicotinamide + Riboflavin + Succinic Acid) is a combination drug, which improves cerebral blood flow, activates metabolic processes in the central nervous system, restores impaired consciousness, promotes regression of neurological symptoms and improvement of cognitive functions of the brain.

NCT ID: NCT04505293 Completed - Head Trauma Clinical Trials

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

Start date: October 5, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect intracranial hematomas (epidural hematomas (EDH) and/or subdural hematomas (SDH)) in patients hospitalized at Mbarara Regional Referral Hospital (MRRH) who have sustained or who are suspected to have sustained head trauma.

NCT ID: NCT03353246 Completed - Head Trauma Clinical Trials

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

Start date: December 11, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect intracranial hematomas (epidural hematomas (EDH) and/or subdural hematomas (SDH)) in patients hospitalized at Duke University Hospital (DUH) who have sustained or who are suspected to have sustained head trauma and have consequently received a brain computed tomography (CT) scan(s).

NCT ID: NCT00219869 Recruiting - Clinical trials for Post-Traumatic Headache

Galantamine in the Treatment of Post-Traumatic Headache

Start date: July 2005
Phase: Phase 4
Study type: Interventional

Most patients with CPTH present with additional major cognitive, behavioral and somatic problems. Most drugs used currently have a negative influence on cognition. Therefore, treatment strategies addressing both the headache and cognitive disturbances in patients with CPTH are necessary. (CPTH; Chronic Post Traumatic Headache).