Head and Neck Carcinoma Clinical Trial
Official title:
Perioperative Nutritional Optimization in Head and Neck Cancer Patients
This randomized clinical trial studies how well Nestle Impact Advanced Recovery works in improving surgery recovery in patients with head and neck cancer. Adding a nutritional supplement, such as Nestle Impact Advanced Recovery to a regular diet before and after head and neck cancer surgery may help to decrease the number of wound complications after surgery.
PRIMARY OBJECTIVES:
I. Assess the effect of perioperative use of Nestle Impact Advanced Recovery (AR) on the rate
of post-operative wound complications within 30 days after major head and neck surgery.
SECONDARY OBJECTIVES:
I. Assess whether sarcopenia is an independent risk factor for the development of
post-operative wound complications.
II. Assess whether Nestle IMPACT AR decreases the rate of other post-operative complications
such as pneumonia, urinary tract infection, deep vein thrombosis, and clostridium difficile
colitis within 30 days of surgery, as well as length of hospital stay.
TERTIARY OBJECTIVES:
I. Assess changes in muscle metabolic gene expression at the time of surgery associated with
sarcopenia and IMAPCT treatment.
OUTLINE: Patients are randomized into 1 of 2 groups.
GROUP I: Patients receive Nestle Impact AR for 5 days before and after surgery in addition to
regular diet.
GROUP I: Patients receive regular diet.
After completion of study, patients are followed up for 30 days post-surgery.
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