Head and Neck Cancer Clinical Trial
Official title:
Investigation of Effects of Physioherapy Interventions on Mechanical Properties of Muscle in Head and Neck Cancer
As the head and neck cancer (HNC) survival rate has increased and therefore, the focus of post-treatments is to improve the quality of patients' life by decreasing the side effects. Treatment of HNC leads to acute and chronic soft tissue damage, and functional loss. However, patients with HNC need having rehabilitation throughout the post-treatment phase so as to improve functional outcomes because of the long term side effects. Chronic shoulder morbidity is one of the complications after surgery due to spinal accesory nerve injury. Moreover, pain, dysphonia, and musculoskeletal impairments are observed in the individuals after the treatments and the patients also have trouble swallowing problems, loss of taste, dry mouth, trismus, nausea, vomiting, and fatigue during and after therapy. Since there is limited research on the usage of manual therapy techniques in HNC patients, this study aims to investigate muscle changes after surgery and the effectiveness of physiotherapy on muscle material behaviour from a biomechanical perspective by using shear wave elastography. In this respect, the hypothesis is: H0: Physical therapy interventions do not impact mechanical properties of muscle, pain, quality of life, cervical and shoulder functionality in HNC patients after neck dissection. H1: Physical therapy interventions will improve mechanical properties of muscle, pain, quality of life, cervical and shoulder functionality in HNC patients after neck dissection.
Status | Recruiting |
Enrollment | 42 |
Est. completion date | November 1, 2023 |
Est. primary completion date | August 20, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - > 18-year-old - Having modified or functional neck dissection - 60< Karnofsky Score - Spinal accesory nerve injury symptoms, such as dropped and winged scapula and decreased shoulder abduction in physical examination. Exclusion Criteria: - Metastasis - Having Radiotherapy- Chemoradiotherapy - Having severe psychological problem - Having previous shoulder injury/ scapular dyskinesia |
Country | Name | City | State |
---|---|---|---|
Turkey | Yeditepe University Hospital | Istanbul |
Lead Sponsor | Collaborator |
---|---|
Yeditepe University | Yeditepe University Hospital |
Turkey,
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* Note: There are 12 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Shoulder pain and disability level | Shoulder Pain and Disability Index | Change from baseline at 6 weeks | |
Primary | Muscle Stiffness | It will be measured by Shear Wave Elastography in relax and contracted state of muscle Muscles: M. Upper Trapezius, M. Sternocleidomastoid, M. Masseter /Bilateral | Change from baseline at 6 weeks | |
Primary | Muscle Thickness | It will be measured by Shear Wave Elastography Muscles: M. Upper Trapezius, M. Sternocleidomastoid, M. Masseter /Bilateral | Change from baseline at 6 weeks | |
Primary | The Quality of Life | The Functional Assessment of Chronic Illness Therapy system of Quality of Life- Head and Neck (FACT H&N Turkish Version) | Change from baseline at 6 weeks | |
Primary | Shoulder Abduction | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Shoulder Flexion | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Shoulder Internal Rotation | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Shoulder External Rotation | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Neck Rotation | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Neck Flexion | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Neck Extension | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Primary | Neck Lateral Flexion | Active range of motion will be measured by goniometer for both side | Change from baseline at 6 weeks | |
Secondary | Mandibular depression | Gap between two incisor teeth with full opened mouth | Change from baseline at 6 weeks |
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