Head and Neck Cancer Clinical Trial
Official title:
Biopsy of Human Tumors for Cancer Stem Cell Characterization: a Feasibility Study
To see if a limited sampling of tumor tissue from human subjects is a feasible way to gather adequate tissue for cancer stem cell quantification.
Status | Completed |
Enrollment | 40 |
Est. completion date | |
Est. primary completion date | October 2012 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria:1. Patients with malignant tumors seen at the Stanford University
Cancer Center. Eligible patients will have a diagnosis of squamous cell carcinoma (HNSCC)
and will have been seen in the Stanford Head and Neck Oncology Program. A decision to
undergo surgery at Stanford will have been made, prior to recruiting patients for the
study, and prior to obtaining the samples during surgery. (Histological confirmation of
the diagnosis need not be made prior to obtaining consent.) 2. A definitive resection of a
malignant tumor is planned. 3. Surgeon judgment that the definitive procedure will not be
compromised by including - FNA - Core needle biopsy - Cup forceps or punch biopsy of<4mm. 4. Informed consent documented prior to procedure |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Stanford University School of Medicine | Stanford | California |
Lead Sponsor | Collaborator |
---|---|
Stanford University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Quantification of the cancer stem cell population by flow cytometry | 1 month | No |
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