Head and Neck Cancer Clinical Trial
Official title:
A Trial Of Lymphatic Mapping And Sentinel Node Lymphadenectomy For Patients With T1 or T2 Clinically N0 Oral Cavity Squamous Cell Carcinoma
RATIONALE: Diagnostic procedures to detect cancer cells in sentinel lymph nodes may help
plan effective cancer treatment.
PURPOSE: Diagnostic trial to study the effectiveness of lymph node mapping and sentinel
lymph node lymphadenectomy in patients who are undergoing surgery to remove early-stage
cancer of the mouth.
OBJECTIVES:
- Determine whether a negative hematoxylin and eosin finding from the lymphatic mapping
and sentinel node lymphadenectomy procedure accurately predicts the negativity of the
other cervical lymph nodes in patients with stage I or II squamous cell carcinoma of
the oral cavity.
- Determine the extent and pattern of disease spread in the nodal bed in these patients.
- Obtain data on the use of immunohistochemistry to assess nodes in these patients.
;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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