HCV Coinfection Clinical Trial
Official title:
Sofosbuvir /Simeprevir/ Daclatasvir/Ribavirin Versus Sofosbuvir /Ombitasvir/ Paritaprevir /Ritonavir/Ribavirin in the Management of Hepatitis C Patients Fauilre to Prior Sofosbuvir/ Daclatasvir (An Open-labeled Randomized Trial)
Now many cases reported failure to HCV treatment with Sofosbuvir/ Daclatasvir. retreat those patients is challenging. So, we aimed to Study the efficacy and safety of Sofosbuvir /Simeprevir/ Daclatasvir/Ribavirin versus Sofosbuvir /ombitasvir/ paritaprevir/ritonavir/ribavirin in the management of hepatitis C patients who failed to prior Sofosbuvir/ Daclatasvir regimens in an open-labeled randomized trial.
HCV management with new DAAs is now promising. However, many cases reporting treatment failure either non-responder or relapse to HCV treatment with Sofosbuvir/ Daclatasvir. retreat those patients is challenging. So, we aimed to Study the efficacy and safety of Sofosbuvir /Simeprevir/ Daclatasvir/Ribavirin versus Sofosbuvir /ombitasvir/ paritaprevir/ritonavir/ribavirin in the management of hepatitis C patients who failed to prior Sofosbuvir/ Daclatasvir regimens in a multicenter open-labeled randomized trial. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02810275 -
Folinic Acid: Supplementation and Therapy
|
Phase 3 | |
| Completed |
NCT03145753 -
Education vs Education Plus Intervention in HIV/HCV Diagnosis (DRIVE 03)
|
N/A | |
| Completed |
NCT01557998 -
Testing and Linkage to Care for Injecting Drug Users in Kenya
|
N/A | |
| Completed |
NCT01335529 -
Boceprevir in HIV-HCV Coinfected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin
|
Phase 2 | |
| Completed |
NCT03499639 -
Ombitasvir/ Paritaprevir / Ritonavir Plus Ribavirin in Management HCV and End-stage Kidney Disease
|
Phase 4 | |
| Completed |
NCT01222611 -
HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With Fosamprenavir
|
Phase 4 | |
| Completed |
NCT03050905 -
Proof of Concept Study To Evaluate the Efficacy and Justification Of OBV/PTV/r and DSV In Adults With Chronic Hepatitis C Virus Genotype 2K/1B
|
Phase 4 | |
| Completed |
NCT02505243 -
Evaluation of RIBAvirin Plasma COncentrations in Patients With Chronic Hepatitis C Infection Routinely Treated With Modern DAA Regimens
|
||
| Recruiting |
NCT02086708 -
Ultrasound Method to Measure Fibrosis of the Liver in Children
|
N/A | |
| Completed |
NCT03508115 -
Changes in Cognition in HCV Patients After Virus Eradication With Direct Antiviral Agents
|
||
| Completed |
NCT03214679 -
Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID)
|
N/A | |
| Completed |
NCT02938013 -
deLIVER: Direct Acting Antiviral Effects on the Liver
|
Phase 4 | |
| Completed |
NCT01900015 -
Changes in Liver Steatosis After Switching to Raltegravir in HIV/HCV Coinfection
|
Phase 4 | |
| Active, not recruiting |
NCT01529073 -
Efficacy of Pegylated Interferon Plus Ribavirin Plus Nitazoxanide in HCV Genotype 4 and HIV Coinfection
|
Phase 2 | |
| Recruiting |
NCT01747772 -
Sonoelastography: Ultrasound Method to Measure Liver Fibrosis
|
N/A | |
| Completed |
NCT02693847 -
Natural History of Liver Cirrhosis Diagnosed by Transient Elastography in HIV/HCV-coinfected Patients
|
||
| Recruiting |
NCT03549312 -
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy
|
Phase 4 | |
| Completed |
NCT03252483 -
Integrating HIV and Hepatitis C Screening in an Urban Emergency Department
|
N/A | |
| Recruiting |
NCT03646396 -
Effect of Sofosbuvir-daclatasuvir on Angiogenesis
|
N/A | |
| Completed |
NCT01335230 -
The Study of Gut Associated Lymphocytes in HIV and HCV/HIV Co-infected Patients
|
N/A |