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Sequential TACE and SBRT Followed by ImmunoTherapy for Downstaging HCC for Hepatectomy — START-FIT  

HCC Clinical Trial

Official title:
Sequential TransArterial Chemoembolization and Stereotactic RadioTherapy Followed by ImmunoTherapy for Downstaging Hepatocellular Carcinoma for Hepatectomy (START-FIT)

Clinical Trial Summary

This study is a prospective phase II, single arm clinical study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of the sequential administration of trans-arterial chemo-embolization (TACE) and stereotactic body radiotherapy (SBRT) with an immune checkpoint inhibitor in hepatocellular carcinoma (HCC) patients.

Clinical Trial Description

All the patients must be registered with the Investigator(s) prior to initiation of treatment. The registration desk will confirm all eligibility criteria and obtain essential information (including patient number). TACE should start within 28 days of study registration and its procedure will be standardised. SBRT screening and planning will be performed by radiation therapists, medical physicists, and oncologists. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03817736
Study type Interventional
Source The University of Hong Kong
Contact
Status Completed
Phase Phase 2
Start date March 1, 2019
Completion date July 26, 2023
View Details
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