Clinical Trials Logo
  1. Home
  2. HBV
  3. NCT04034368

A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) and Intolerant to Entecavir

HBV Clinical Trial

Official title:
A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) or Intolerant to Entecavir

Clinical Trial Summary

This is a multicenter, single arm, open label, historical control pilot Study to the antiviral efficacy and safety of Suboptimal Responders to Entecavir Switching to TAF Treatment at week 48 (investigate the rates of complete virological response on switching to TAF in patients with Suboptimal response or ETV intolerance to standard ETV= 0.5 mg monotherapy).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04034368
Study type Interventional
Source First Hospital of Jilin University
Contact Yanhang Gao
Phone 15804303019
Email 15804303019@qq.com
Status Not yet recruiting
Phase Phase 4
Start date August 2019
Completion date June 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT05442437 - Clinical Study of hUC-MSCs Treating Decompensated Liver Cirrhosis With HBV Early Phase 1
Completed NCT04519710 - Specific Anti-HBV Vaccine Response After Vaccination in Patients Requiring Anti-CD20 Monoclonal Antibodies N/A
Recruiting NCT04562051 - Stratified vs Routine Prophylaxis in Living Kidney Transplantation From HBsAg+ Donors to HBsAg- Recipients
Recruiting NCT04683341 - Tenofovir Alafenamide in HBV Related Decompensated Liver Phase 4
Active, not recruiting NCT02344680 - Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
Completed NCT02044068 - Hepatitis B Virus Vertical Transmission From HIV-HBV Co-infected Women N/A
Completed NCT03239353 - A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Entecavir Extended Release (XR) in Healthy Subjects Phase 1
Recruiting NCT04904835 - Access HBV Assays - European Union (EU) Clinical Trial Protocol -
Terminated NCT04059198 - Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus Phase 2
Not yet recruiting NCT05293158 - Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept Study N/A
Not yet recruiting NCT05028322 - Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond to the Usual Vaccine Regimen Phase 2
Completed NCT02312531 - Prevention for Mother-to-infant Transmission of HBV N/A
Not yet recruiting NCT01556815 - Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma Phase 2
Recruiting NCT05786859 - The Efficacy and Safety of Rifaximin Treatment Early Phase 1
Recruiting NCT05951751 - The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM) N/A
Not yet recruiting NCT06307808 - Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination
Completed NCT03149627 - Chronic Hepatitis B Virus Clinical Epidemiology in a Representative Sample of Zambian Adults
Recruiting NCT04886336 - The Impact of Tenofovir Alafenamide on Profiles of Body Weight and Metabolic Features in Chronic Hepatitis B Patients.
Recruiting NCT04568265 - A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B Phase 2
Terminated NCT02826018 - A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection Phase 1