Hay Fever Clinical Trial
Official title:
Evaluation of High Speed Laser Doppler Imaging Technology to Quantify Skin Prick Tests in Allergic Volunteers
Skin prick tests (SPT) are commonly used in daily allergological practice to assess skin
reactivity to allergens. Multiple factors can contribute to non-optimal results of
conventional wheal and flare measurement (CWFM) of SPT such as inaccurate measurements,
observer-dependency and absence of traceability.
This study aims to evaluate the quantification of SPT by a novel High Speed Laser Doppler
Imaging (HSL-DI) and to compare it with CWFM. First, SPT with birch and/or grass pollen
extracts as well as positive and negative controls will be performed in 20 volunteers (11
atopics, 9 non-atopics) to establish the characteristics (cut-off, optimal reading time and
allergen concentration) of HSL-DI analysis based on two parameters ("area" and "flow"
measurement). In a second step, fifty patients will be tested with birch and grass pollen
extracts at optimal allergen concentration and time window. Analysis of SPT by HSL-DI and
CWFM will be compared.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00658918 -
To Assess the Safety of Ciclesonide, Applied as a Nasal Spray at Three Dose Levels, in the Treatment of Perennial Allergic Rhinitis in Pediatrics (BY9010/M1-405)
|
Phase 3 | |
| Active, not recruiting |
NCT05960266 -
Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control Study
|
Early Phase 1 | |
| Completed |
NCT00574210 -
PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)
|
Phase 2 | |
| Completed |
NCT00384475 -
A Study of Ciclesonide Nasal Spray in Patients 18 Years and Older With Seasonal Allergic Rhinitis (BY9010/M1-413)
|
Phase 3 | |
| Completed |
NCT06457269 -
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
|
N/A | |
| Completed |
NCT01506375 -
Safety of gpASIT+TM Subcutaneously Administered to Hay Fever Patients With or Without Immunoregulating Adjuvant
|
Phase 2 | |
| Completed |
NCT01137357 -
Probiotics for Reduction Of Markers In Subjects With Allergy
|
N/A | |
| Completed |
NCT00261287 -
Safety and Tolerability of Ciclesonide Nasal Spray in Patients With Perennial Allergic Rhinitis (2-5 Years Old) (BY9010/M1-416)
|
Phase 3 | |
| Completed |
NCT00659594 -
Study Using the Environmental Exposure Chamber (EEC) to Assess the Onset of Action of Ciclesonide, Applied as a Nasal Spray in Treatment of Seasonal Allergic Rhinitis (BY9010/M1-406)
|
Phase 3 | |
| Active, not recruiting |
NCT00247520 -
Safety and Efficacy Study of rEV131 in Allergic Rhinitis
|
Phase 1/Phase 2 | |
| Completed |
NCT00163514 -
Safety and Effectiveness of Ciclesonide Nasal Spray in Children (6 to 11 Years) With Perennial Allergic Rhinitis (BY9010/M1-403)
|
Phase 3 | |
| Completed |
NCT04326309 -
Audio Data Collection for Identification and Classification of Coughing
|
||
| Completed |
NCT00305487 -
Safety and Efficacy of Ciclesonide in Pediatric Patients (6 to 11 Years of Age) With Seasonal Allergic Rhinitis (BY9010/M1-417)
|
Phase 3 | |
| Completed |
NCT02932774 -
Randomized, Double Blind, Parallel Group, Placebo Controlled, Multi-Center Study of the Efficacy and Safety of Cetirizine HCl Syrup vs. Loratadine Syrup vs. Placebo in Treatment of Children With Seasonal Allergic Rhinitis (SAR)
|
Phase 4 | |
| Completed |
NCT00163488 -
Safety of Ciclesonide Nasal Spray Administered With Inhaled Fluticasone Dipropionate/Salmeterol in Adults With Perennial Allergic Rhinitis (BY9010/M1-409)
|
Phase 3 | |
| Not yet recruiting |
NCT03724240 -
Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis
|
Phase 3 | |
| Completed |
NCT01660737 -
Observational Study With PASCALLERG ® in Patients With Hay Fever
|
||
| Completed |
NCT00659503 -
Study Using the Environmental Exposure Unit (EEU) to Assess the Onset of Action of Ciclesonide, Applied as a Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (BY9010/M1-407)
|
Phase 3 | |
| Completed |
NCT01024608 -
Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)
|
Phase 3 | |
| Completed |
NCT02560948 -
Clinical Efficacy and Safety of a Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis
|
Phase 3 |