Gynoid Lipodystrophy Clinical Trial
Official title:
Effect of Shockwave Therapy Associated With an Aerobic Exercise Program on the Degree of Severity of Gynoid Lipodystrophy in Women: a Randomized Controlled Trial
The purpose of the present study is to evaluate the effects of six sessions of aerobic exercise associated with shock waves therapy in the severity of gynoid lipodystrophy.
The Gynoid Lipodystrophy (GL) is considered to be a subcutaneous tissue disorder that causes
changes in visible skin topography in the form of protrusions and depressions, mainly located
in the lower limbs and abdominal region. It is a non-inflammatory and degenerative condition
whose etiology has not been fully elucidated until now, although it can be explained by
varied theories: the hormonal ,that is related to estrogen, the morphological one, based on
alterations of the adipose tissue that is related to the interlobular septa of connective
tissue that interconnects the subcutaneous adipose lobes, these septa are thin and have
perpendicular projections, which favors the deposition of adipose tissue and its expansion to
the surface of the dermis. The last one is about microcirculation deficits that can lead to
intracellular edema and reduction of lymphatic drainage.
Shock wave therapy appears to be a safe and effective therapy to act in this disorder. It
generates mechanical pressure waves in the tissues, promoting cavitation phenomena that
produces lipolysis by destroying the cell membrane of adipocytes, increasing blood flow in
the region, and stimulating lymphatic drainage.
On the other hand, there are studies that report that improvement in the appearance of GL is
associated with a decrease in subcutaneous adipose tissue. Physiologically, aerobic physical
exercise has the capacity to decrease body fat, taking into account that the oxidation
reactions of fatty acids are enhanced, with moderate intensity exercise.
In this sense, it may be beneficial to associate Shockwave Therapy and Physical Exercise to
reduce GL severity, so this study aims to analyze the effect of radial shock wave therapy in
association with the performance of an aerobic exercise program, in female subjects, in the
degree of GL severity in the gluteal region and ⅓ proximal posterior of the thighs.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01671839 -
Study of the Cabochon System for Improvement in the Appearance of Cellulite
|
N/A |