Study on the Antiaging Effect of Chinese Herb Drink

Gynecological Disorders Clinical Trial

Official title:

Study on the Antiaging Effect of Chinese Herb Drink

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02634242
• Other study ID #: CS08008
• Status: Completed
• Phase: N/A
• First received: December 8, 2015
• Last updated: December 15, 2015
• Start date: April 2008
• Est. completion date: April 2009

Study information

• Verified date: December 2015
• Source: Chung Shan Medical University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: National Health Research Institutes
• Study type: Interventional

Clinical Trial Summary

The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

Description:

Background: Si-Wu-Tang (SWT) is a well-known traditional Chinese medicine (TCM) and widely used for treating various gynecological disorders. The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

Methods: Sixty healthy voluntary subjects were recruited and assigned into two groups, who drank 125 mL of placebo (n=30) or SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between. During the initial, 3rd, 6th, 10th, and 13th months anthropometric measurements were performed as well as fasting blood samples were drawn for various biochemical assays. Abdominal ultrasonic and skin examination were performed at the initial, 6th and 13th months.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: April 2009
• Est. primary completion date: April 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• healthy adults

Exclusion Criteria:

• exclusion criteria were history of smoking, alcoholism

• pregnant or lactating women,

• chronic diseases, hepatic or renal dysfunction.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator)

Related Conditions & MeSH terms

• Genital Diseases, Female
• Gynecological Disorders

Intervention

Other:
• Si-Wu-Tang (SWT)
The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.
• placebo
The purpose of the current study was to check the physiological improvement of placebo on liver and skin and also the antioxidation in healthy adults.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chung Shan Medical University

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Skin sebum content		6 months	No
Other	Skin hydration		6 months	No
Other	Skin surface water loss		6 months	No
Other	Skin melanin index		6 months	No
Other	Skin elasticity		6 months	No
Primary	Total thiobarbituric acid reactive substances (TBARS)		6 months	No
Secondary	Glutathione content (GSH)		6 months	No
Secondary	Total antioxidant capacity (TEAC)activities.		6 months	No
Secondary	Superoxide dismutase (SOD) activity		6 months	No
Secondary	GPx and glutathione reductase (GR) activity		6 months	No
Secondary	Catalase		6 months	No
Secondary	Glutamic oxaloacetic transaminase (GOT)		6 months	No
Secondary	Glutamic pyruvic transaminase (GPT)		6 months	No