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Magnesium Sulfate; Postoperative Nausea and Vomiting; Laparoscopic Surgery

Gynecologic Disease Clinical Trial

Official title:
The Effect of Intravenous Magnesium Sulfate on Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynecologic Surgery

Clinical Trial Summary

Postoperative nausea and vomiting (PONV) is commonly accompanied in patients undergoing surgery under general anesthesia. The patients undergoing laparoscopic gynecologic surgery have multiple risk factors for developing PONV such as female gender, nonsmoker, postoperative opioids, and laparoscopic surgery. Thus, it is important to prevent PONV in these patients.

Clinical Trial Description

Magnesium is a N-methyl-D-aspartate (NMDA) antagonist that is known to be effective in reducing opioid consumption and controlling postoperative pain. This opioid reducing effect can be associated with reduction of the incidence of PONV. However, the effect of magnesium on preventing PONV have not been investigated before. Thus, the investigators hypothesized that intraoperative infusion of magnesium will be effective in preventing PONV in patients undergoing laparoscopic gynecologic surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03541915
Study type Interventional
Source Gangnam Severance Hospital
Contact
Status Not yet recruiting
Phase N/A
Start date December 1, 2018
Completion date May 30, 2019
View Details
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