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Gynecologic Disease clinical trials

View clinical trials related to Gynecologic Disease.

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NCT ID: NCT06425484 Recruiting - Gynecologic Disease Clinical Trials

The Comparison of Effectiveness Between Epidural Combined Bilateral US TAP Block Versus Epidural Alone for Gynaecology Operation.

Start date: May 31, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare effectiveness between epidural combined with TAP block versus epidural alone in gynaecology operation participant .The main question[s] it aims to answer are: - what is the pain score for both groups - what is the requirement of epidural infusion between the 2 groups Participants will be given general anesthesia for the operation with the epidural insertion prior to induction. Patient will be randomized into epidural plus TAP block or epidural alone for the study. The US TAP block will be given at the end of operation prior to extubation. Researchers will compare pain score, epidural infusion requirment between the two groups.

NCT ID: NCT06412861 Recruiting - Sedation Clinical Trials

Propofol-ketamine or Propofol-fentanyl for Procedural Sedation in the Short-term Gynecological Case

Start date: April 20, 2024
Phase: N/A
Study type: Interventional

Comparison of fentanyl-propofol and ketamine-propofol combination for sedation in brief gynecological cases Our study aimed to evaluate ketamine-propofol and fentanyl-propofol combinations in short-term gynecological cases in terms of hemodynamic parameters, recovery, complications, patient and physician comfort.

NCT ID: NCT05897385 Recruiting - Postoperative Pain Clinical Trials

Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery

Start date: August 22, 2023
Phase: N/A
Study type: Interventional
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NCT ID: NCT05518812 Recruiting - Gynecologic Disease Clinical Trials

Carboprost (Hemabate) for Fibroid Resection

Start date: July 12, 2022
Phase: Early Phase 1
Study type: Interventional

The purpose of this research study is to determine if low-dose (i.e., a fraction of what is commonly used) carboprost (Hemabate) helps facilitate fibroid removal (myomectomy).

NCT ID: NCT05509244 Recruiting - Gynecologic Disease Clinical Trials

Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Laparoscopic Gynecology Surgery

Start date: September 9, 2022
Phase: N/A
Study type: Interventional

Acetaminophen and ibuprofen has been safely used for a long time and reduces postoperative pain and opioid dosages. Investigators are planning to compare the efficacy of 1) acetaminophen only and 2) acetaminophen and ibuprofen combination at postoperative pain after laparoscopic gynecologic surgery.

NCT ID: NCT05125692 Recruiting - Gynecologic Disease Clinical Trials

Vaginal Repair of Post Cesarean Istmocele

OWarda
Start date: September 4, 2021
Phase: N/A
Study type: Interventional

20 WOMEN WITH SYMPTOMATIC POSTCESAREAN ISTHMOCELE (NICHE) WILL BE RECRUITED EVALUATED AND SUBJECTED TO A VAGINAL REPAIR OF THE DEFECT, RESULTS WILL BE ANALYZED.

NCT ID: NCT04963751 Recruiting - Gynecologic Disease Clinical Trials

ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling

Start date: September 8, 2022
Phase: N/A
Study type: Interventional

The Investigator propose a randomized trial that will assess whether participant involvement in pre-operative counseling for ERAS improves post-surgical pain scores. The Investigator will also assess participant compliance to ERAS-prescribed medications, and functionality (return to school). Each participant who is enrolled in the study will be assigned to 1) pre-operative counseling with participant's caregiver or 2) caregiver-only counseling.

NCT ID: NCT04708353 Recruiting - Gynecologic Disease Clinical Trials

Oral Pregabalin Premedication for Postoperative Pain Relief

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

Pain management after gynecological surgeries is essential for early mobilization of the patient, decrease postoperative complication and hospital stay. The use of opioids is associated with adverse effects such as nausea, vomiting, ileus, pruritus, sedation and respiratory depression. Previous studies stated that pregabalin has been used to reduce pre-operative anxiety, acute postoperative pain, postoperative opioid requirements, postoperative nausea, vomiting and postoperative delirium. The most effective dose of pregabalin to relief postoperative pain with least side effect is still under trial. In this study we will compare between two different doses of pregabalin when given as oral premedication in patients undergoing gynecological surgeries under spinal anesthesia regarding postoperative pain in order to reduce opioids consumption and subsequently avoid opioid-related adverse effects.

NCT ID: NCT04700761 Recruiting - Gynecologic Disease Clinical Trials

Opioid-free Anesthesia in Gynecologic Surgery

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Post-operative nausea and vomiting (PONV) is common for the patients undergoing laparoscopic gynecologic surgery. PONV is a major factor for patient dissatisfaction, delayed patient recovery and increased medical expenses. Opioid-reducing anesthetic regimen is known to decrease PONV and facilitate early recovery after surgery (ERAS) and has been widely accepted recently. In this study, the researchers intend to investigate whether opioid-free anesthesia effectively reduces PONV, and whether it is clinically safe and feasible.

NCT ID: NCT03988348 Recruiting - Gynecologic Disease Clinical Trials

Perioperative Outcome of Infraumbilical Versus a Modified Intraumbilical Direct Trocar Insertion

Start date: August 4, 2019
Phase: N/A
Study type: Interventional

Laparoscopic surgery is now a well-established alternative to open surgery for many gynecological disorders owing to its faster wound healing, shorter hospital stay, less postoperative pain, and better cosmetic results. Postoperative scar cosmoses is a critical issue for women, especially for young women. These scars may have negative impacts, such as psychological consequences. The symptoms associated with the wound, such as pain, tenderness, and itching, can be induced by the scars