Clinical Trials Logo
  1. Home
  2. Gut Microbiome
  3. NCT04117321

Mother-infant Microbiota Transmission and Its Link to the Health of the Baby

Gut Microbiome Clinical Trial

Official title:
Mother-infant Microbiota Transmission and Its Link to the Health of the Baby

Clinical Trial Summary

The human intestinal tract harbors a diverse and complex microbial community, known as gut microbiota, which is critical in sustaining physiology, metabolism, nutrition and immune function. Dysbiosis of gut microbiota has been linked with obesity, hyperglycemia, hyperlipidemia, inflammatory bowel disease and other chronic inflammatory diseases. Gut microbiota is affected by host genetic markup, diet and life style; and therefore varied by human races and geographical locations. The development of gut microbiota starts before birth. The infant's microbiome can impact on human health in later life. The microbiome of pregnant women are associated with early-life microbiota of their offspring as well as growth, neurodevelopment and the development of allergic and neurocognitive disorders. Early childhood, when the microbiota is less mature and more malleable, is a golden age for microbiota manipulation to prevent disease. Studying microbiota at this golden age also allow us to dissect the development of a faulty microbiota and identify therapeutic targets to reverse it and cure diseases that are already developed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04117321
Study type Observational
Source Chinese University of Hong Kong
Contact Jessica Ching
Phone +852 26373260
Email jessicaching@cuhk.edu.hk
Status Recruiting
Phase
Start date September 23, 2019
Completion date October 2, 2027
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05793112 - INF108F in Infants With Food Protein Induced Proctocolitis Phase 4
Active, not recruiting NCT04327141 - Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women N/A
Recruiting NCT05655910 - Enhanced Nutritional Optimization in LVAD Trial N/A
Recruiting NCT03325855 - Fecal Microbiota Transplant National Registry
Active, not recruiting NCT05931471 - Yogurt and GI Health N/A
Recruiting NCT03797417 - Gut Microbiome and Metabolic Pathways Changes in Vitiligo
Withdrawn NCT06006416 - Effect of Fenugreek Fibre on Gut Microbiome Phase 3
Recruiting NCT06206486 - The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation
Completed NCT02655250 - Neonatal Microbiome Validity Study
Recruiting NCT05670288 - Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury
Not yet recruiting NCT03975764 - Fecal Microbiota in Preterm Birth
Completed NCT03219931 - NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants Phase 4
Recruiting NCT04447365 - The Correlation Between Gut Microbiome-host Interaction and Ventricular Arrhythmias.
Recruiting NCT04466072 - Gut Microbiome and Ventricular Arrhythmias
Not yet recruiting NCT06130137 - Gut Microbiome in People Living With HIV and HBV
Recruiting NCT06260579 - Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity N/A
Completed NCT04511052 - Probiotics for Enhanced Tissue Carotenoid Status in Premenopausal Women Phase 1/Phase 2
Active, not recruiting NCT06424691 - Infant Restore: Efficacy of Microbiome Analysis and Education N/A
Recruiting NCT06404749 - Fungal Fiber for Gut Health N/A
Not yet recruiting NCT06433310 - Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study Early Phase 1