Impact of GH Measurements on GHD Diagnosis

Status Completed

Clinical Trial Summary

Human growth hormone (hGH) provocation test is an essential tool to assess growth hormone deficiency in children and young adults. It is important to have a robust and reliable method to determine the hGH peak of stimulation. This work aimed to compare three common automated immunoassays for hGH measurements and to assess whether there are still result-related differences influencing clinical decision.

Clinical Trial Description

The investigators analysed GH provocative test of 41 young patients (median age: 12 years) from Pediatric Department of Montpellier Hospital, (26 boys and 15 girls), admitted for follow-up or for suspicion of growth hormone deficiency. Serum GH of peak concentrations were compared using three automated immunoanalyses : COBAS 8000 e602 (ROCHE Diagnostics), IDS-iSYS (IDS immunodiagnostic systems) and Liaison XL (Diasorin S.A.). ;

Study Design

Related Conditions & MeSH terms

Growth Hormone Deficiency

Clinical Trial Details

NCT number	NCT04508673
Study type	Observational
Source	University Hospital, Montpellier
Contact
Status	Completed
Phase
Start date	April 1, 2019
Completion date	November 25, 2019

View Details

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