Granulomatous Mastitis Clinical Trial
Official title:
Evaluation of Topical Steroids and Surgical Treatment for Idiopathic Granulomatous Mastitis
This study evaluates the clinical response rate of topical steroids in the treatment of idiopathic granulomatous mastitis in female adults. Half of the participants will receive topical steroid and the other half will receive local wide surgical excision.
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast disease of
unknown etiology.It may present with many findings that clinically and radiologically mimic
breast cancer.
Although IGM as a disease has been known for nearly four decades, the optimal treatment
approach has not been established. Surgical intervention in the form of wide surgical
excision was the mainstay of treatment before 1980, and is still performed depending on local
expertise and preference.
Currently,surgical treatment and systemic steroid treatment are frequently employed. With the
consideration of side effects of longterm systemic (oral) steroid usage, topical steroid
without systemic use were assessed and showed satisfactory curative effect. But the data
concerning the use of topical steroid therapy are still very limited.
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