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Clinical Trial Summary

This study evaluates the clinical response rate of topical steroids in the treatment of idiopathic granulomatous mastitis in female adults. Half of the participants will receive topical steroid and the other half will receive local wide surgical excision.


Clinical Trial Description

Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast disease of unknown etiology.It may present with many findings that clinically and radiologically mimic breast cancer.

Although IGM as a disease has been known for nearly four decades, the optimal treatment approach has not been established. Surgical intervention in the form of wide surgical excision was the mainstay of treatment before 1980, and is still performed depending on local expertise and preference.

Currently,surgical treatment and systemic steroid treatment are frequently employed. With the consideration of side effects of longterm systemic (oral) steroid usage, topical steroid without systemic use were assessed and showed satisfactory curative effect. But the data concerning the use of topical steroid therapy are still very limited. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02959580
Study type Interventional
Source Peking Union Medical College Hospital
Contact Yanna Zhang, M.D.
Phone 86-10-69158703
Email pumchzyn@sohu.com
Status Recruiting
Phase Phase 4
Start date January 1, 2017
Completion date September 2020

See also
  Status Clinical Trial Phase
Completed NCT04540237 - Serum Cytokine Values in Patients With Granulomatous Mastitis
Completed NCT04596046 - Could Intralesional Steroid be the Novel Treatment for Granulomatous Mastitis? N/A
Recruiting NCT03766997 - Local Steroid Treatment for Idiopathic Granulomatous Mastitis (LSTIGM) Phase 4
Completed NCT04543149 - Immune Cells in Patients With Granulomatous Mastitis
Completed NCT03724903 - Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis N/A