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Decidual Stromal Cells as Treatment for Acute Graft Versus Host Disease, a Phase 1-2 Study

Graft vs Host Disease Clinical Trial

Official title:
Decidual Stromal Cells as Treatment for Acute Graft Versus Host Disease

Clinical Trial Summary

The purpose of this study is to evaluate safety and efficacy using decidual stromal cell therapy for graft versus host disease after allogeneic hematopoietic stem cell transplantation. The hypothesis to be tested is that the cells are safe to infuse and that they have a positive clinical effect.

Clinical Trial Description

Patients with GVHD grade 2-4, will receive decidual stromal cells at approximately 1-2x10^6 cells/kg at one or more occasions dependent on clinical response. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02172937
Study type Interventional
Source Karolinska Institutet
Contact Olle Ringdén, MD, PhD
Phone +46858582672
Email olle.ringden@ki.se
Status Recruiting
Phase Phase 1/Phase 2
Start date January 2011
Completion date December 2016
View Details
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