Clinical Trials Logo
  1. Home
  2. Gluten Sensitivity
  3. NCT03771443

Assessment of the Effect of Gluten Free Toothpaste on the Ulcerative Events in Children With Celiac Disease

Gluten Sensitivity Clinical Trial

Official title:
Assessment of the Effect of Gluten Free Toothpaste on the Ulcerative Events in Children With Celiac Disease (Before and After Pilot Study)

Clinical Trial Summary

Celiac disease (CD) is the most common genetically based food intolerance in the world, with a prevalence among approximately 1% of the general population (Guandalini & Assiri, 2014). CD is a frequent disorder among Egyptian children, both in the general population and in at-risk groups(Abu-Zekry et al., 2008). It is estimated that the incidence of CD is 3 to13 cases per1000, with a higher prevalence among first-degree relatives of patients with CD.Lifelong adherence to a strict gluten free diet (GFD) remains the only available treatment for patients with CD and typically results in a complete return to health. Nevertheless, gluten is not found only in diet, Gluten is commonly used as a binder in products like medication, cosmetics, oral and skin care, and even children's toys. Gluten is found also in toothpastes and other oral health products and it can be swallowed by mistake and initiate immune response(Anon, n.d.). Unfortunately, there is no gluten free toothpaste available in the Egyptian market and it is very expensive if we bought it from Europe or USA. The tube will cost nearly 10 dolars .As a result, the production and availability of gluten free toothpaste in Egypt has become mandatory.

Clinical Trial Description

production of an experimental gluten free toothpaste and providing it for children with celiac disease ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03771443
Study type Interventional
Source Cairo University
Contact
Status Completed
Phase Phase 3
Start date July 21, 2019
Completion date January 21, 2020
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05555446 - Bovine Colostrum to Prevent Absorption of Gluten Early Phase 1
Completed NCT03288831 - Changes in Intestinal Permeability 4 Hours After Gluten Challenge N/A
Completed NCT04247737 - Gluten Free Diet in IBS N/A
Active, not recruiting NCT03678935 - Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients N/A
Completed NCT03543540 - Bioequivalence Study of Nexvax2 in Subjects With Celiac Disease Phase 1
Completed NCT01485341 - Gluten Sensitivity in Non-Celiac Patients Phase 3
Completed NCT01558557 - Gluten Free Diet in People With Schizophrenia: A Pilot Study N/A
Recruiting NCT05803408 - RCT: Effect of Late vs Early Introduction of Gluten-free Oats on Patients With Newly Diagnosed Celiac Disease. N/A
Recruiting NCT03183609 - Confirmatory Efficacy Trial of a Gluten-Free Diet in a Subgroup of Persons With Schizophrenia Who Have High Levels of IgG Anti-Gliadin Antibodies (AGA IG) N/A
Completed NCT03020511 - Effects of Ancient Grains-based Diet in a Closed Community N/A
Recruiting NCT05209568 - Immune Responses to Gluten N/A
Recruiting NCT05644782 - Dietary Approach to Mild-to-moderate Psoriasis N/A
Completed NCT03638544 - Reduced Content of Gluten Diet on Patients With Irritable Bowel Syndrome (Pro.Ali.Fun.) N/A
Recruiting NCT03089632 - The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms N/A
Active, not recruiting NCT03644069 - A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD) Phase 2
Recruiting NCT02431585 - Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics. N/A
Completed NCT03268720 - Influence of the Immunosystem in Non-celiac Glutensensitivity N/A
Suspended NCT03462979 - Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease N/A
Not yet recruiting NCT03329534 - Gluten Related Disorders in Barrett's Esophagus N/A