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Glottic Carcinoma clinical trials

View clinical trials related to Glottic Carcinoma.

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NCT ID: NCT05688488 Recruiting - Glottic Carcinoma Clinical Trials

Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

Start date: May 5, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal cords after the surgery on the bilateral vocal cord endoscopically.

NCT ID: NCT05679856 Recruiting - Glottic Carcinoma Clinical Trials

Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer

VC-Larynx
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The primary objective of this prospective randomized clinical trial is to assess non inferiority in terms of local control achieved with single vocal cord hypofractionated radiotherapy compared to standard of care whole laryngeal radiotherapy in patients with T1aN0 glottic cancer . Secondary objectives include overall survival rate and to compare the Voice Handicap Index score between the 2 arms as well as acute and late toxicities. Patients are randomized in 1:1 ratio.

NCT ID: NCT04908696 Recruiting - Glottic Carcinoma Clinical Trials

Clinical Treatments in Specialized Disease of Laryngeal Carcinoma (LC) and Hypopharyngeal Carcinoma (HPC)

Start date: December 1, 2020
Phase:
Study type: Observational

For early stage laryngeal carcinoma and hypohparyngeal carcinoma (T1 and T2), transoral laser microsurgery, open partial laryngectomy, radiotherapy, and transoral robotic surgery were performed according to NCCN guidelines (2020). For advanced stage laryngeal carcinoma and hypohparyngeal carcinoma (T3 and T4), surgical treatment ± postoperative adjuvant therapy, chemoradiotherapy, neoadjuvant therapy + radiotherapy/chemoradiotherapy, or neoadjuvant therapy + surgery + radiotherapy or chemoradiotherapy performed according to NCCN guidelines (2020). This study plan to analyze the clinical ouctomes of different treatment for the same T stage disease. The overall survival rate, disease specific survival, disease free survival, local control, regional control, and laryngeal function preservation rate were analyzed in this study.

NCT ID: NCT04447456 Completed - Glottic Carcinoma Clinical Trials

Comparison of Voice Results at 5 Years of Treatment of Glottic Squamous Cell Carcinoma T1 by Surgery Versus Radiotherapy

VO Qual
Start date: November 3, 2020
Phase:
Study type: Observational

Patients with early-stage squamous cell carcinomas of the vocal cord can be treated in an equivalent way in terms of carcinology by surgery or radiotherapy. The study will be to analyse the vocal outcome at 5 years of these two types of management in order to define whether one is superior to the other on this criterion of voice quality after treatment.

NCT ID: NCT03548285 Active, not recruiting - Glottic Carcinoma Clinical Trials

Stereotactic Ablative Radiotherapy for Early-stage Glottic Larynx Cancer

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

The goal of treatment with radiation therapy is to deliver as high of a dose as possible to the target (tumor), while minimizing the dose to the normal tissues where late-side effects can drastically affect patient quality of life.