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Efficacy, Safety and PK/PD of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) (NewPLACE) — NewPLACE  

Glomerulonephritis Clinical Trial

Official title:
A Phase IIa, Open-Label, 2-Arm Multicenter Clinical Trial to Evaluate the Efficacy, Safety and PK/PD of the Human Anti-CD38 Antibody MOR202 in Anti-PLA2R Antibody Positive Membranous Nephropathy (NewPLACE)

Clinical Trial Summary

This 2-arm, multi-center, open-label, parallel-group phase II trial will assess the efficacy, safety and pharmacokinetics/pharmacodynamics of the human antibody MOR202 in subjects with anti-PLA2R antibody-positive membranous nephropathy indicated for immunosuppressive therapy

Clinical Trial Description

After treatment, subjects will enter a repeat treatment period (3 months) if necessary; and a final follow-up period of 15 to 18 months ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04733040
Study type Interventional
Source HI-Bio
Contact
Status Completed
Phase Phase 2
Start date January 20, 2021
Completion date December 14, 2023
View Details
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