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Glomerulonephritis, IGA clinical trials

View clinical trials related to Glomerulonephritis, IGA.

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NCT ID: NCT00318474 Terminated - IgA Nephropathy Clinical Trials

Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy

Start date: January 2002
Phase: Phase 3
Study type: Interventional

IgA nephropathy (IgAN) is the most common type of glomerulonephritis worldwide. 15-40% of individuals diagnosed with IgAN, including children, will eventually progress to chronic renal insufficiency (CRI) and end stage renal disease (ESRD). The study is to evaluate the safety and benefits of MMF in patients with IgAN who have been pre-treated (and continue to be treated) with angiotensin converting enzyme inhibitors (ACEi) and fish oil supplements (FOS).

NCT ID: NCT00301600 Completed - IGA Nephropathy Clinical Trials

Mycophenolate Mofetil Versus Intravenous Cyclophosphamide Pulses in the Treatment of Crescentic IgA Nephropathy

Start date: January 2003
Phase: N/A
Study type: Interventional

A single-center random parallel study to compare the efficacy and safety of Mycophenolate mofetil versus intravenous Cyclophosphamide pulses in the treatment of crescentic IgA nephropathy

NCT ID: NCT00006137 Completed - Clinical trials for IGA Glomerulonephritis

Pilot Study of Enalapril and Renal Function in Patients With IgA Nephropathy

Start date: May 2000
Phase: N/A
Study type: Interventional

OBJECTIVES: I. Determine the most sensitive outcome measures (functional or morphological) of a progressive renal injury in patients with IgA nephropathy. II. Determine which of these patients are destined to progress to further injury in order to target them for therapy. III. Elucidate the determinants of progression in those patients who exhibit evidence of either increasing impairment of ultrafiltration capacity or ongoing destruction of nephrons.

NCT ID: NCT00004448 Completed - Clinical trials for IGA Glomerulonephritis

Alternate Day Prednisone or Daily Fish Oil Supplements in Patients With Immunoglobulin A Nephropathy

Start date: November 1997
Phase: Phase 2
Study type: Interventional

OBJECTIVES: Evaluate the efficacy of alternate day prednisone versus daily fish oil supplements in slowing or preventing the decline in renal function in children, adolescents, and young adults with moderate to severe immunoglobulin A nephropathy.

NCT ID: NCT00004305 Completed - Clinical trials for IGA Glomerulonephritis

Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis

Start date: January 1998
Phase: N/A
Study type: Observational

OBJECTIVES: I. Determine whether allelic differences associated with the fourth component of complement, type-1 complement receptor expressed on erythrocytes, and Fc receptor FcgRIII contribute to the pathogenesis of IgA glomerulonephritis (IgA-N). II. Compare genetic anomalies of these key components in immune complex processing and clearance between juvenile vs adult onset IgA-N vs normal controls.